Research workbench
AlphaFold monomer V2.0 prediction for 2-isopropylmalate synthase (B5FI58)
Analyse AlphaFold monomer V2.0 prediction for 2-isopropylmalate synthase (B5FI58) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- B5FI58
- Type
- protein
- Length
- 523 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x35612D34a32C306CA4fc1edA9360D1F717e25950
- Molecule
- 2-isopropylmalate synthase
- UniProt
- B5FI58
- Pockets
- 6 · best druggability 0.64
Structure
1 distinct chain · 46% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 2-isopropylmalate synthase | protein | 523 | 46% helix, 21% strand | B5FI58 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 407 | 0.64 | 0.78 | 29 | empty |
| 2 | 125 | 0.55 | 0.83 | 18 | empty |
| 3 | 110 | 0.43 | 0.77 | 18 | empty |
| 4 | 63 | 0.41 | 0.81 | 17 | empty |
| 5 | 118 | 0.38 | 0.74 | 17 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B5FI58
- Elsewhere: UniProt B5FI58 · AlphaFold DB B5FI58
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