Research workbench
AlphaFold monomer V2.0 prediction for 2-isopropylmalate synthase (C0Z9C8)
Analyse AlphaFold monomer V2.0 prediction for 2-isopropylmalate synthase (C0Z9C8) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- C0Z9C8
- Type
- protein
- Length
- 512 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x97EfFf2d74994e28D3b69b1503Bd9c292B2Df480
- Molecule
- 2-isopropylmalate synthase
- UniProt
- C0Z9C8
- Pockets
- 6 · best druggability 0.75
Structure
1 distinct chain · 45% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 2-isopropylmalate synthase | protein | 512 | 45% helix, 22% strand | C0Z9C8 |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 588 | 0.75 | 0.82 | 64 | empty |
| 2 | 504 | 0.68 | 0.79 | 46 | empty |
| 3 | 126 | 0.54 | 0.82 | 21 | empty |
| 4 | 175 | 0.52 | 0.78 | 22 | empty |
| 5 | 94 | 0.45 | 0.80 | 19 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C0Z9C8
- Elsewhere: UniProt C0Z9C8 · AlphaFold DB C0Z9C8
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