Research workbench
AlphaFold monomer V2.0 prediction for 2-isopropylmalate synthase (A5EP79)
Analyse AlphaFold monomer V2.0 prediction for 2-isopropylmalate synthase (A5EP79) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- A5EP79
- Type
- protein
- Length
- 523 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xB35df660264f41795De49C83276C108A4ba91ADE
- Molecule
- 2-isopropylmalate synthase
- UniProt
- A5EP79
- Pockets
- 6 · best druggability 0.53
Structure
1 distinct chain · 46% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 2-isopropylmalate synthase | protein | 523 | 46% helix, 21% strand | A5EP79 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 119 | 0.53 | 0.82 | 18 | empty |
| 2 | 187 | 0.49 | 0.76 | 25 | empty |
| 3 | 75 | 0.40 | 0.79 | 23 | empty |
| 4 | 84 | 0.37 | 0.77 | 21 | empty |
| 5 | 83 | 0.33 | 0.74 | 19 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A5EP79
- Elsewhere: UniProt A5EP79 · AlphaFold DB A5EP79
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