Research workbench
AlphaFold monomer V2.0 prediction for pyruvate kinase (Q44473)
Analyse AlphaFold monomer V2.0 prediction for pyruvate kinase (Q44473) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q44473
- Type
- protein
- Length
- 482 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd34DD3DBbC95510c872aD7e41A651f650Bd07472
- Molecule
- Pyruvate kinase
- UniProt
- Q44473
- Pockets
- 5 · best druggability 0.65
Structure
1 distinct chain · 38% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pyruvate kinase | protein | 482 | 38% helix, 23% strand | Q44473 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 54 | 0.65 | 0.95 | 24 | empty |
| 2 | 339 | 0.59 | 0.77 | 52 | empty |
| 3 | 168 | 0.50 | 0.78 | 22 | empty |
| 4 | 94 | 0.43 | 0.79 | 21 | empty |
| 5 | 55 | 0.25 | 0.73 | 14 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q44473
- Elsewhere: UniProt Q44473 · AlphaFold DB Q44473
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