Research workbench
AlphaFold monomer V2.0 prediction for pyruvate kinase, cytosolic isozyme (P22200)
Analyse AlphaFold monomer V2.0 prediction for pyruvate kinase, cytosolic isozyme… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P22200
- Type
- protein
- Length
- 510 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x507b0cF5c2F663afF8A05761eBf4e0Bf457a72Fb
- Molecule
- Pyruvate kinase, cytosolic isozyme
- UniProt
- P22200
- Pockets
- 5 · best druggability 0.68
Structure
1 distinct chain · 40% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pyruvate kinase, cytosolic isozyme | protein | 510 | 40% helix, 24% strand | P22200 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 664 | 0.68 | 0.76 | 69 | empty |
| 2 | 373 | 0.65 | 0.80 | 48 | empty |
| 3 | 186 | 0.56 | 0.80 | 28 | empty |
| 4 | 103 | 0.45 | 0.79 | 21 | empty |
| 5 | 106 | 0.34 | 0.73 | 22 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22200
- Elsewhere: UniProt P22200 · AlphaFold DB P22200
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