Research workbench
AlphaFold monomer V2.0 prediction for alpha-ketoglutaric semialdehyde dehydrogenase 1 (Q1JUP4)
Analyse AlphaFold monomer V2.0 prediction for alpha-ketoglutaric semialdehyde… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q1JUP4
- Type
- protein
- Length
- 481 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7a1388B6Aad67B04634A32f63b8A6D6005eab86c
- Molecule
- Alpha-ketoglutaric semialdehyde dehydrogenase 1
- UniProt
- Q1JUP4
- Pockets
- 3 · best druggability 0.57
Structure
1 distinct chain · 40% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Alpha-ketoglutaric semialdehyde dehydrogenase 1 | protein | 481 | 40% helix, 22% strand | Q1JUP4 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 194 | 0.57 | 0.80 | 27 | empty |
| 2 | 299 | 0.56 | 0.76 | 34 | empty |
| 3 | 84 | 0.39 | 0.77 | 16 | empty |
Compared structures
- 5X5U · Crystal structure of alpha-ketoglutarate-semialdehyde dehydrogenase (KGSADH) complexed… · an experimental structure of the same protein · chain A against B, TM-score 0.99
- 5X5T · Crystal structure of alpha-ketoglutarate semialdehyde dehydrogenase (KGSADH) from… · an experimental structure of the same protein · chain A against B, TM-score 0.99
- 5X5U · Crystal structure of alpha-ketoglutarate-semialdehyde dehydrogenase (kgsadh) complexed… · an experimental structure of the same protein · chain A against A, TM-score 0.98
- 5X5T · Crystal structure of alpha-ketoglutarate semialdehyde dehydrogenase (kgsadh) from… · an experimental structure of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q1JUP4
- Elsewhere: UniProt Q1JUP4 · AlphaFold DB Q1JUP4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.