Research workbench
AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 4E-2 (O74743)
Analyse AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O74743
- Type
- protein
- Length
- 243 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xA777E42419704A95462d8413746e87F7381Bd58e
- Molecule
- Eukaryotic translation initiation factor 4E-2
- UniProt
- O74743
- Pockets
- 3 · best druggability 0.57
Structure
1 distinct chain · 29% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Eukaryotic translation initiation factor 4E-2 | protein | 243 | 29% helix, 24% strand | O74743 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 193 | 0.57 | 0.80 | 24 | empty |
| 2 | 130 | 0.41 | 0.75 | 21 | empty |
| 3 | 71 | 0.39 | 0.79 | 16 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O74743
- Elsewhere: UniProt O74743 · AlphaFold DB O74743
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