Research workbench
AlphaFold monomer V2.0 prediction for isocitrate dehydrogenase [NADP] (P33197)
Analyse AlphaFold monomer V2.0 prediction for isocitrate dehydrogenase [NADP] (P33197) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P33197
- Type
- protein
- Length
- 496 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6Ed09D80e98fE15DE51C9E7a8896AbF1f2365C3e
- Molecule
- Isocitrate dehydrogenase [NADP]
- UniProt
- P33197
- Pockets
- 3 · best druggability 0.82
Structure
1 distinct chain · 35% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Isocitrate dehydrogenase [NADP] | protein | 496 | 35% helix, 24% strand | P33197 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 247 | 0.82 | 0.94 | 31 | empty |
| 2 | 407 | 0.58 | 0.74 | 39 | empty |
| 3 | 141 | 0.42 | 0.76 | 21 | empty |
Compared structures
- 2D1C · Crystal Structure Of TT0538 protein from Thermus thermophilus HB8 · an experimental structure of the same protein · chain A against A, TM-score 0.98
- 2D1C · Crystal structure of TT0538 protein from thermus thermophilus HB8 · an experimental structure of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P33197
- Elsewhere: UniProt P33197 · AlphaFold DB P33197
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