Research workbench
AlphaFold monomer V2.0 prediction for erad-associated E3 ubiquitin- protein ligase component HRD3A (Q9LM25)
Analyse AlphaFold monomer V2.0 prediction for erad-associated E3 ubiquitin- protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q9LM25
- Type
- protein
- Length
- 678 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x41f982d1Ab404B1F39f5162365b91bF104CE6a14
- Molecule
- Erad-associated E3 ubiquitin-protein ligase component HRD3A
- UniProt
- Q9LM25
- Pockets
- 8 · best druggability 0.81
Structure
1 distinct chain · 66% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Erad-associated E3 ubiquitin-protein ligase component HRD3A | protein | 678 | 66% helix, 1% strand | Q9LM25 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 881 | 0.81 | 0.84 | 89 | empty |
| 2 | 185 | 0.65 | 0.85 | 24 | empty |
| 3 | 128 | 0.51 | 0.80 | 19 | empty |
| 4 | 181 | 0.49 | 0.76 | 32 | empty |
| 5 | 96 | 0.38 | 0.76 | 20 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9LM25
- Elsewhere: UniProt Q9LM25 · AlphaFold DB Q9LM25
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