Research workbench
AlphaFold monomer V2.0 prediction for hydroxyisourate hydrolase (Q8S3J3)
Analyse AlphaFold monomer V2.0 prediction for hydroxyisourate hydrolase (Q8S3J3) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q8S3J3
- Type
- protein
- Length
- 560 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xC54bE124303Fe567caF2bCE4af35f677b73CbF9D
- Molecule
- Hydroxyisourate hydrolase
- UniProt
- Q8S3J3
- Pockets
- 8 · best druggability 0.84
Structure
1 distinct chain · 48% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Hydroxyisourate hydrolase | protein | 560 | 48% helix, 14% strand | Q8S3J3 |
Pockets
8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 219 | 0.84 | 0.96 | 28 | empty |
| 2 | 139 | 0.52 | 0.79 | 21 | empty |
| 3 | 65 | 0.50 | 0.86 | 18 | empty |
| 4 | 102 | 0.43 | 0.78 | 21 | empty |
| 5 | 57 | 0.39 | 0.81 | 15 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8S3J3
- Elsewhere: UniProt Q8S3J3 · AlphaFold DB Q8S3J3
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