Research workbench
AlphaFold monomer V2.0 prediction for gasdermin-E (Q9Z2D3)
Analyse AlphaFold monomer V2.0 prediction for gasdermin-E (Q9Z2D3) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q9Z2D3
- Type
- protein
- Length
- 512 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0D671490EE06E75975e90D7F99F73B20BE618744
- Molecule
- Gasdermin-E
- UniProt
- Q9Z2D3
- Pockets
- 10 · best druggability 0.82
Structure
1 distinct chain · 38% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Gasdermin-E | protein | 512 | 38% helix, 26% strand | Q9Z2D3 |
Pockets
10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 729 | 0.82 | 0.86 | 66 | empty |
| 2 | 352 | 0.71 | 0.84 | 47 | empty |
| 3 | 256 | 0.58 | 0.79 | 24 | empty |
| 4 | 99 | 0.57 | 0.86 | 24 | empty |
| 5 | 78 | 0.46 | 0.82 | 18 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Z2D3
- Elsewhere: UniProt Q9Z2D3 · AlphaFold DB Q9Z2D3
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