AlphaFold monomer V2.0 prediction for granzyme H (P20718)

Structure

1 distinct chain · 10% helix, 35% strand (DSSP).

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

• 3TK9 · Crystal structure of human granzyme H · an experimental structure of the same protein · chain A against A, TM-score 0.91
• 3TK9 · Crystal structure of human granzyme H · an experimental structure of the same protein · chain A against A, TM-score 0.91
• 3TJV · Crystal structure of human granzyme H with a peptidyl substrate · an experimental structure of the same protein · chain A against A, TM-score 0.91
• 3TJV · Crystal structure of human granzyme H with a peptidyl substrate · an experimental structure of the same protein · chain A against A, TM-score 0.91
• 3TJU · Crystal structure of human granzyme H with an inhibitor · an experimental structure of the same protein · chain A against A, TM-score 0.91
• 3TJU · Crystal structure of human granzyme H with an inhibitor · an experimental structure of the same protein · chain A against A, TM-score 0.91
• 4GAW · Crystal structure of active human granzyme H · an experimental structure of the same protein · chain A against B, TM-score 0.91
• 4GAW · Crystal structure of active human granzyme H · an experimental structure of the same protein · chain A against B, TM-score 0.91

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P20718
• Elsewhere: UniProt P20718 · AlphaFold DB P20718