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AlphaFold monomer V2.0 prediction for PDZ domain-containing protein GIPC2 (Q8TF65)

Analyse AlphaFold monomer V2.0 prediction for PDZ domain-containing protein GIPC2… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q8TF65
Type
protein
Length
315 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xe43D264c0E4229A2c42bC24F7Fed41a1fCf1938d
Molecule
PDZ domain-containing protein GIPC2
UniProt
Q8TF65
Pockets
2 · best druggability 0.70

Structure

1 distinct chain · 29% helix, 23% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APDZ domain-containing protein GIPC2protein31529% helix, 23% strandQ8TF65

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
16230.700.7864empty
21850.510.7731empty

Compared structures

  • 3GGE · Crystal structure of the PDZ domain of PDZ domain-containing protein GIPC2 · an experimental structure of the same protein · chain A against C, TM-score 0.29
  • 3GGE · Crystal structure of the PDZ domain of PDZ domain-containing protein GIPC2 · an experimental structure of the same protein · chain A against C, TM-score 0.29

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