Research workbench
AlphaFold monomer V2.0 prediction for fibroblast growth factor receptor 2 (Q91147)
Analyse AlphaFold monomer V2.0 prediction for fibroblast growth factor receptor 2… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q91147
- Type
- protein
- Length
- 729 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf87a97E0A4bB354D834857B14296240B167cbe70
- Molecule
- Fibroblast growth factor receptor 2
- UniProt
- Q91147
- Pockets
- 6 · best druggability 0.78
Structure
1 distinct chain · 22% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fibroblast growth factor receptor 2 | protein | 729 | 22% helix, 22% strand | Q91147 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1049 | 0.78 | 0.80 | 105 | empty |
| 2 | 249 | 0.55 | 0.77 | 32 | empty |
| 3 | 225 | 0.52 | 0.76 | 27 | empty |
| 4 | 138 | 0.39 | 0.74 | 20 | empty |
| 5 | 95 | 0.35 | 0.74 | 19 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q91147
- Elsewhere: UniProt Q91147 · AlphaFold DB Q91147
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