Research workbench
AlphaFold monomer V2.0 prediction for flap endonuclease 1 (O50123)
Analyse AlphaFold monomer V2.0 prediction for flap endonuclease 1 (O50123) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O50123
- Type
- protein
- Length
- 343 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x3aEE739629077DbA5E2D0D9F4655D362a335420a
- Molecule
- Flap endonuclease 1
- UniProt
- O50123
- Pockets
- 5 · best druggability 0.60
Structure
1 distinct chain · 51% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Flap endonuclease 1 | protein | 343 | 51% helix, 11% strand | O50123 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 199 | 0.60 | 0.82 | 32 | empty |
| 2 | 164 | 0.42 | 0.74 | 18 | empty |
| 3 | 52 | 0.39 | 0.81 | 14 | empty |
| 4 | 135 | 0.39 | 0.74 | 18 | empty |
| 5 | 88 | 0.36 | 0.75 | 20 | empty |
Compared structures
- 1MC8 · Crystal Structure of Flap Endonuclease-1 R42E mutant from Pyrococcus horikoshii · an experimental structure of the same protein · chain A against B, TM-score 0.86
- 1MC8 · Crystal structure of flap endonuclease-1 R42E mutant from pyrococcus horikoshii · an experimental structure of the same protein · chain A against B, TM-score 0.86
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O50123
- Elsewhere: UniProt O50123 · AlphaFold DB O50123
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