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AlphaFold monomer V2.0 prediction for polycomb protein eed (Q921E6)

Analyse AlphaFold monomer V2.0 prediction for polycomb protein eed (Q921E6) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: Q921E6
Type: protein
Length: 441 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xbDA05C32aD6eE153C8C5A78dfa48d7Ba25694fea
Molecule: Polycomb protein eed
UniProt: Q921E6
Pockets: 2 · best druggability 0.76

Structure

1 distinct chain · 5% helix, 39% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Polycomb protein eed	protein	441	5% helix, 39% strand	Q921E6

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	356	0.76	0.87	34	empty
2	90	0.35	0.74	19	empty

Compared structures

2QXV · Structural basis of EZH2 recognition by EED · an experimental structure of the same protein · chain A against A, TM-score 0.80
2QXV · Structural basis of EZH2 recognition by eed · an experimental structure of the same protein · chain A against A, TM-score 0.80

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q921E6
Elsewhere: UniProt Q921E6 · AlphaFold DB Q921E6

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