Research workbench
AlphaFold monomer V2.0 prediction for DNA polymerase I (P74933)
Analyse AlphaFold monomer V2.0 prediction for DNA polymerase I (P74933) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P74933
- Type
- protein
- Length
- 997 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x136D36477109D2950D3fC03D98b07D430b523238
- Molecule
- DNA polymerase I
- UniProt
- P74933
- Pockets
- 13 · best druggability 0.73
Structure
1 distinct chain · 49% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA polymerase I | protein | 997 | 49% helix, 12% strand | P74933 |
Pockets
13 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1004 | 0.73 | 0.76 | 91 | empty |
| 2 | 512 | 0.69 | 0.79 | 49 | empty |
| 3 | 360 | 0.59 | 0.77 | 39 | empty |
| 4 | 331 | 0.57 | 0.76 | 33 | empty |
| 5 | 215 | 0.50 | 0.76 | 26 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P74933
- Elsewhere: UniProt P74933 · AlphaFold DB P74933
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