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UniProt V9H0D0

LINE-1 retrotransposon endonuclease (V9H0D0)

LINE-1 retrotransposon endonuclease (UniProt V9H0D0), EC 2.7.7.49: 2 experimental structures on GenesisL1, 3 ligands bound, 8 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
V9H0D0
Protein
LINE-1 retrotransposon endonuclease
EC
2.7.7.49
Experimental structures
2
Predicted models
0
Ligands
3
Pockets
8 · 1 record with a druggable one

Structures

2 records of V9H0D0 in the MolNFT archive: 2 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
8SP5LINE-1 retrotransposon endonuclease domain complex with Mn2+x-ray diffractionA, BMN, SO47 (best 0.59)
8SP7LINE-1 retrotransposon endonuclease domain complex with tranexamic acidx-ray diffractionAAMH, SO41 (best 0.33)

Ligands

  • SO4 · Sulfate ion · in 2 records
  • AMH · Trans-4-aminomethylcyclohexane-1-carboxylic acid · in 1 record
  • MN · Manganese (II) ion · in 1 record

Elsewhere

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