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UniProt U6KL66

Dihydroorotate dehydrogenase (quinone), mitochondrial (U6KL66)

Dihydroorotate dehydrogenase (quinone), mitochondrial (UniProt U6KL66), EC 1.3.5.2: 4 experimental structures on GenesisL1, 3 ligands bound, 35 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
U6KL66
Protein
Dihydroorotate dehydrogenase (quinone), mitochondrial
EC
1.3.5.2
Experimental structures
4
Predicted models
0
Ligands
3
Pockets
35 · 2 records with a druggable one

Structures

4 records of U6KL66 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6AJ5Crystal structure of ligand-free type DHODH from Eimeria tenellax-ray diffractionA, B, C, DFMN, ORO18 (best 0.83)
6AJ5Crystal structure of ligand-free type dhodh from eimeria tenellax-ray diffractionA, B, C, DFMN, ORO—
6AJECrystal structure of DHODH in complex with ferulenol from Eimeria tenellax-ray diffractionA, B, C, DFMN, ORO, 9AU17 (best 0.86)
6AJECrystal structure of dhodh in complex with ferulenol from eimeria tenellax-ray diffractionA, B, C, DFMN, ORO, 9AU—

Ligands

  • FMN · Flavin mononucleotide · in 4 records
  • ORO · Orotic acid · in 4 records
  • 9AU · 4-oxidanyl-3-[(2~{E},6~{E})-3,7,11-trimethyldodeca-2,6, 10-trienyl]chromen-2-one · in 2 records

Elsewhere

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