GL1X · GenesisL1 explorer

UniProt R4NFR6

Neuraminidase (R4NFR6)

Neuraminidase (UniProt R4NFR6), EC 3.2.1.18: 9 experimental structures on GenesisL1, 5 ligands bound, 3 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
R4NFR6
Protein
Neuraminidase
EC
3.2.1.18
Experimental structures
9
Predicted models
0
Ligands
5
Pockets
3 · 2 records with a druggable one

Structures

9 records of R4NFR6 in the MolNFT archive: 9 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5JYYStructure-based tetravalent zanamivir with potent inhibitory activity against drug-resistant…x-ray diffractionA——
5L14The crystal structure of neuraminidase from A/Shanghai/2/2013 (H7N9) influenza virusx-ray diffractionANAG, CA—
5L14The crystal structure of neuraminidase from A/SHANGHAI/2/2013 (H7N9) influenza virusx-ray diffractionANAG, CA—
5L15The crystal structure of neuraminidase in complex with oseltamivir from A/Shanghai/2/2013 (H7N9)…x-ray diffractionANAG, CA, G39—
5L15The crystal structure of neuraminidase in complex with oseltamivir from A/SHANGHAI/2/2013 (H7N9)…x-ray diffractionANAG, CA, G39—
5L17The crystal structure of neuraminidase in complex with zanamivir from A/Shanghai/2/2013 (H7N9)…x-ray diffractionANAG, CA, ZMR2 (best 0.61)
5L17The crystal structure of neuraminidase in complex with zanamivir from A/SHANGHAI/2/2013 (H7N9)…x-ray diffractionANAG, CA, ZMR—
5L18The crystal structure of neuraminidase in complex with sialic acid from A/Shanghai/2/2013 (H7N9)…x-ray diffractionANAG, CA, SIA1 (best 0.62)
5L18The crystal structure of neuraminidase in complex with sialic acid from A/SHANGHAI/2/2013 (H7N9)…x-ray diffractionANAG, CA, SIA—

Ligands

  • CA · Calcium ion · in 8 records
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 8 records
  • G39 · (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy) cyclohex-1-ene-1-carboxylic acid · in 2 records
  • SIA · N-acetyl-alpha-neuraminic acid · in 2 records
  • ZMR · Zanamivir · in 2 records

Elsewhere

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