UniProt Q9Y7D0
Lovastatin nonaketide synthase, enoyl reductase component lovC (Q9Y7D0)
Lovastatin nonaketide synthase, enoyl reductase component lovC (UniProt Q9Y7D0), EC 2.3.1.161: 8 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9Y7D0
- Protein
- Lovastatin nonaketide synthase, enoyl reductase component lovC
- EC
- 2.3.1.161
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 5 · 2 records with a druggable one
Structures
9 records of Q9Y7D0 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3B6Z | Lovastatin polyketide enoyl reductase (LovC) complexed with 2'-phosphoadenosyl isomer of… | x-ray diffraction | A | — | — |
| 3B6Z | Lovastatin polyketide enoyl reductase (lovc) complexed with 2'- phosphoadenosyl isomer of… | x-ray diffraction | A | — | — |
| 3B70 | Crystal structure of Aspergillus terreus trans-acting lovastatin polyketide enoyl reductase (LovC)… | x-ray diffraction | A | — | — |
| 3B70 | Crystal structure of aspergillus terreus trans-acting lovastatin polyketide enoyl reductase (lovc)… | x-ray diffraction | A | — | — |
| 3GQV | Lovastatin polyketide enoyl reductase (LovC) mutant K54S with bound NADP | x-ray diffraction | A | — | — |
| 3GQV | Lovastatin polyketide enoyl reductase (lovc) mutant K54S with bound NADP | x-ray diffraction | A | — | — |
| 7CPY | Lovastatin nonaketide synthase with LovC | electron microscopy | C, D | — | 2 (best 0.79) |
| 7CPY | Lovastatin nonaketide synthase with lovc | electron microscopy | C, D | — | — |
| Q9Y7D0 | AlphaFold monomer V2.0 prediction for lovastatin nonaketide synthase, enoyl reductase component… | predicted | A | — | 3 (best 0.77) |
Experiment against prediction
- 3B6Z chain A against the predicted model Q9Y7D0: TM-score 1.00, RMSD 0.43 Å
- 3B6Z chain A against the predicted model Q9Y7D0: TM-score 1.00, RMSD 0.43 Å
- 3GQV chain A against the predicted model Q9Y7D0: TM-score 0.99, RMSD 0.79 Å
- 3GQV chain A against the predicted model Q9Y7D0: TM-score 0.99, RMSD 0.79 Å
- 3B70 chain A against the predicted model Q9Y7D0: TM-score 0.99, RMSD 0.82 Å
- 3B70 chain A against the predicted model Q9Y7D0: TM-score 0.99, RMSD 0.82 Å
- 7CPY chain C against the predicted model Q9Y7D0: TM-score 0.99, RMSD 0.82 Å
- 7CPY chain C against the predicted model Q9Y7D0: TM-score 0.99, RMSD 0.82 Å
- 7CPY chain D against the predicted model Q9Y7D0: TM-score 0.99, RMSD 0.82 Å
Elsewhere
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