UniProt Q9Y6X9
MORC family CW-type zinc finger protein 2 (Q9Y6X9)
MORC family CW-type zinc finger protein 2 (UniProt Q9Y6X9): 6 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 38 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q9Y6X9
- Protein
- MORC family CW-type zinc finger protein 2
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 38 · 4 records with a druggable one
Structures
7 records of Q9Y6X9 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5OF9 | Crystal structure of human MORC2 (residues 1-603) | x-ray diffraction | A, B | ZN, ANP, MG | 11 (best 0.75) |
| 5OF9 | Crystal structure of human MORC2 (residues 1-603) | x-ray diffraction | A, B | ZN, ANP, MG | — |
| 5OFA | Crystal structure of human MORC2 (residues 1-603) with spinal muscular atrophy mutation T424R | x-ray diffraction | B, A | ZN, ANP, MG | 12 (best 0.80) |
| 5OFA | Crystal structure of human MORC2 (residues 1-603) with spinal muscular atrophy mutation T424R | x-ray diffraction | B, A | ZN, ANP, MG | — |
| 5OFB | Crystal structure of human MORC2 (residues 1-603) with spinal muscular atrophy mutation S87L | x-ray diffraction | B, A | ZN, ATP, MG | 11 (best 0.81) |
| 5OFB | Crystal structure of human MORC2 (residues 1-603) with spinal muscular atrophy mutation S87L | x-ray diffraction | B, A | ZN, ATP, MG | — |
| Q9Y6X9 | AlphaFold monomer V2.0 prediction for ATPase MORC2 (Q9Y6X9) | predicted | A | — | 4 (best 0.72) |
Ligands
Experiment against prediction
- 5OFA chain A against the predicted model Q9Y6X9: TM-score 0.99, RMSD 0.77 Å
- 5OFA chain A against the predicted model Q9Y6X9: TM-score 0.99, RMSD 0.77 Å
- 5OFA chain B against the predicted model Q9Y6X9: TM-score 0.99, RMSD 0.93 Å
- 5OFA chain B against the predicted model Q9Y6X9: TM-score 0.99, RMSD 0.93 Å
- 5OF9 chain A against the predicted model Q9Y6X9: TM-score 0.99, RMSD 1.05 Å
- 5OF9 chain A against the predicted model Q9Y6X9: TM-score 0.99, RMSD 1.05 Å
- 5OFB chain A against the predicted model Q9Y6X9: TM-score 0.98, RMSD 1.14 Å
- 5OFB chain A against the predicted model Q9Y6X9: TM-score 0.98, RMSD 1.14 Å
- 5OF9 chain B against the predicted model Q9Y6X9: TM-score 0.98, RMSD 1.21 Å
- 5OF9 chain B against the predicted model Q9Y6X9: TM-score 0.98, RMSD 1.21 Å
Elsewhere
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