UniProt Q9Y5P6
Mannose-1-phosphate guanyltransferase beta (Q9Y5P6)
Mannose-1-phosphate guanyltransferase beta (UniProt Q9Y5P6), EC 2.7.7.13: 6 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 27 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9Y5P6
- Protein
- Mannose-1-phosphate guanyltransferase beta
- EC
- 2.7.7.13
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 27 · 3 records with a druggable one
Structures
7 records of Q9Y5P6 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7D72 | Cryo-EM structures of human GMPPA/GMPPB complex bound to GDP-Mannose | electron microscopy | K, I, E, F, G, H, J, L | GDD, MG | 12 (best 0.70) |
| 7D72 | Cryo-EM structures of human GMPPA/GMPPB complex bound to GDP-mannose | electron microscopy | K, I, E, F, G, H, J, L | GDD, MG | — |
| 7D73 | Cryo-EM structure of GMPPA/GMPPB complex bound to GTP (State I) | electron microscopy | E, F, G, I, J, K, L, H | GTP | 8 (best 0.71) |
| 7D73 | Cryo-EM structure of GMPPA/GMPPB complex bound to GTP (state I) | electron microscopy | E, F, G, I, J, K, L, H | GTP | — |
| 7D74 | Cryo-EM structure of GMPPA/GMPPB complex bound to GTP (state II) | electron microscopy | E, F, G, H, I, J, K, L | GTP | 7 (best 0.77) |
| 7D74 | Cryo-EM structure of GMPPA/GMPPB complex bound to GTP (state II) | electron microscopy | E, F, G, H, I, J, K, L | GTP | — |
| Q9Y5P6 | AlphaFold monomer V2.0 prediction for mannose-1-phosphate guanyltransferase beta (Q9Y5P6) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7D72 chain G against the predicted model Q9Y5P6: TM-score 0.99, RMSD 0.83 Å
- 7D72 chain G against the predicted model Q9Y5P6: TM-score 0.99, RMSD 0.83 Å
- 7D73 chain J against the predicted model Q9Y5P6: TM-score 0.99, RMSD 0.82 Å
- 7D73 chain J against the predicted model Q9Y5P6: TM-score 0.99, RMSD 0.82 Å
- 7D73 chain G against the predicted model Q9Y5P6: TM-score 0.99, RMSD 0.86 Å
- 7D73 chain G against the predicted model Q9Y5P6: TM-score 0.99, RMSD 0.86 Å
- 7D72 chain J against the predicted model Q9Y5P6: TM-score 0.98, RMSD 0.87 Å
- 7D72 chain J against the predicted model Q9Y5P6: TM-score 0.98, RMSD 0.87 Å
- 7D72 chain H against the predicted model Q9Y5P6: TM-score 0.98, RMSD 0.88 Å
- 7D72 chain H against the predicted model Q9Y5P6: TM-score 0.98, RMSD 0.88 Å
Elsewhere
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