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UniProt Q9Y5N5

Methyltransferase N6AMT1 (Q9Y5N5)

Methyltransferase N6AMT1 (UniProt Q9Y5N5), EC 2.1.1.-: 13 experimental structures on GenesisL1, 3 ligands bound, 6 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q9Y5N5
Protein
Methyltransferase N6AMT1
EC
2.1.1.-
Experimental structures
13
Predicted models
0
Ligands
3
Pockets
6 · 2 records with a druggable one

Structures

13 records of Q9Y5N5 in the MolNFT archive: 13 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6H1DCrystal structure of C21orf127-TRMT112 in complex with SAHx-ray diffractionA——
6H1DCrystal structure of C21ORF127-TRMT112 in complex with sahx-ray diffractionA——
6H1ECrystal structure of C21ORF127-TRMT112 in complex with sah and H4 peptidex-ray diffractionA——
6K0XStructure of N6AMT1-TRMT112 complex with SAMx-ray diffractionA——
6KHSCrystal structure of HEMK2/TRMT112 in complex with sah and meqx-ray diffractionA——
6KMRCrystal structure of human N6amt1-Trm112 in complex with SAM (space group P6122)x-ray diffractionB——
6KMRCrystal structure of human N6AMT1-TRM112 in complex with SAM (space group P6122)x-ray diffractionB——
6KMSCrystal structure of human N6amt1-Trm112 in complex with SAM (space group I422)x-ray diffractionC, D——
6KMSCrystal structure of human N6AMT1-TRM112 in complex with SAM (space group I422)x-ray diffractionC, D——
6PEDCrystal structure of HEMK2-TRMT112 complexx-ray diffractionAUNX—
8CNCStructure of compound 1 bound KMT9x-ray diffractionA6D63 (best 0.76)
8QDGcompound 1a bound KMT9 crystal structurex-ray diffractionASDU3 (best 0.71)
Q9Y5N5AlphaFold monomer V2.0 prediction for methyltransferase N6AMT1 (Q9Y5N5)———

Ligands

  • 6D6 · 5'-{[(3S)-3-amino-3-carboxypropyl](3-aminopropyl) amino}-5'-deoxyadenosine · in 1 record
  • SDU · (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[(3~{S})-pyrrolidin-3-yl]amino]-2-azanyl-butanoic acid · in 1 record
  • UNX · Unknown atom or ion · in 1 record

Elsewhere

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