UniProt Q9Y5K5
Ubiquitin carboxyl-terminal hydrolase isozyme L5 (Q9Y5K5)
Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UniProt Q9Y5K5): 19 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y5K5
- Protein
- Ubiquitin carboxyl-terminal hydrolase isozyme L5
- Experimental structures
- 19
- Predicted models
- 1
- Pockets
- 3 · 0 records with a druggable one
Structures
20 records of Q9Y5K5 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3A7S | Catalytic domain of UCH37 | x-ray diffraction | A | — | — |
| 3A7S | Catalytic domain of UCH37 | x-ray diffraction | A | — | — |
| 3IHR | Crystal Structure of Uch37 | x-ray diffraction | A | — | — |
| 3IHR | Crystal structure of UCH37 | x-ray diffraction | A | — | — |
| 3RII | Crystal structure of the catalytic domain of UCHL5, a proteasome-associated human deubiquitinating… | x-ray diffraction | A, B | — | — |
| 3RII | Crystal structure of the catalytic domain of UCHL5, a proteasome- associated human deubiquitinating… | x-ray diffraction | A, B | — | — |
| 3RIS | Crystal structure of the catalytic domain of UCHL5, a proteasome-associated human deubiquitinating… | x-ray diffraction | A, B, C, D | — | — |
| 3RIS | Crystal structure of the catalytic domain of UCHL5, a proteasome- associated human deubiquitinating… | x-ray diffraction | A, B, C, D | — | — |
| 3TB3 | Crystal structure of the UCH domain of UCH-L5 with 6 residues deleted | x-ray diffraction | A, B | — | — |
| 3TB3 | Crystal structure of the uch domain of uch-L5 with 6 residues deleted | x-ray diffraction | A, B | — | — |
| 4UEL | UCH-L5 in complex with ubiquitin-propargyl bound to the RPN13 DEUBAD domain | x-ray diffraction | A | — | — |
| 4UEL | Uch-L5 in complex with ubiquitin-propargyl bound to the RPN13 deubad domain | x-ray diffraction | A | — | — |
| 4UEM | UCH-L5 in complex with the RPN13 DEUBAD domain | x-ray diffraction | A | — | — |
| 4UEM | Uch-L5 in complex with the RPN13 deubad domain | x-ray diffraction | A | — | — |
| 4UF5 | Crystal structure of UCH-L5 in complex with inhibitory fragment of INO80G | x-ray diffraction | A | — | — |
| 4UF5 | Crystal structure of uch-L5 in complex with inhibitory fragment of INO80G | x-ray diffraction | A | — | — |
| 4UF6 | UCH-L5 in complex with ubiquitin-propargyl bound to an activating fragment of INO80G | x-ray diffraction | A, D, G, J | — | — |
| 4UF6 | Uch-L5 in complex with ubiquitin-propargyl bound to an activating fragment of INO80G | x-ray diffraction | A, D, G, J | — | — |
| 4WLP | Crystal structure of UCH37-nfrkb inhibited deubiquitylating complex | x-ray diffraction | A | — | — |
| Q9Y5K5 | AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase isozyme L5 (Q9Y5K5) | predicted | A | — | 3 (best 0.44) |
Experiment against prediction
- 4UEM chain A against the predicted model Q9Y5K5: TM-score 0.98, RMSD 0.91 Å
- 4UEM chain A against the predicted model Q9Y5K5: TM-score 0.98, RMSD 0.91 Å
- 3TB3 chain A against the predicted model Q9Y5K5: TM-score 0.98, RMSD 0.97 Å
- 3TB3 chain A against the predicted model Q9Y5K5: TM-score 0.98, RMSD 0.97 Å
- 4UEL chain A against the predicted model Q9Y5K5: TM-score 0.97, RMSD 1.28 Å
- 4UEL chain A against the predicted model Q9Y5K5: TM-score 0.97, RMSD 1.28 Å
- 3A7S chain A against the predicted model Q9Y5K5: TM-score 0.96, RMSD 1.20 Å
- 3A7S chain A against the predicted model Q9Y5K5: TM-score 0.96, RMSD 1.20 Å
- 3RII chain A against the predicted model Q9Y5K5: TM-score 0.95, RMSD 1.72 Å
- 3RII chain A against the predicted model Q9Y5K5: TM-score 0.95, RMSD 1.72 Å
Elsewhere
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