UniProt Q9Y535
DNA-directed RNA polymerase III subunit RPC8 (Q9Y535)
DNA-directed RNA polymerase III subunit RPC8 (UniProt Q9Y535): 25 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 21 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q9Y535
- Protein
- DNA-directed RNA polymerase III subunit RPC8
- Experimental structures
- 25
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 21 · 14 records with a druggable one
Structures
26 records of Q9Y535 in the MolNFT archive: 25 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7A6H | Cryo-EM structure of human apo RNA Polymerase III | electron microscopy | G | ZN | 2 (best 0.80) |
| 7A6H | Cryo-EM structure of human apo RNA polymerase III | electron microscopy | G | ZN | — |
| 7AE1 | Cryo-EM structure of human RNA Polymerase III elongation complex 1 | electron microscopy | G | — | 1 (best 0.77) |
| 7AE1 | Cryo-EM structure of human RNA polymerase III elongation complex 1 | electron microscopy | G | — | — |
| 7AE3 | Cryo-EM structure of human RNA Polymerase III elongation complex 3 | electron microscopy | G | — | 1 (best 0.77) |
| 7AE3 | Cryo-EM structure of human RNA polymerase III elongation complex 3 | electron microscopy | G | — | — |
| 7AEA | Cryo-EM structure of human RNA Polymerase III elongation complex 2 | electron microscopy | G | — | 1 (best 0.78) |
| 7AEA | Cryo-EM structure of human RNA polymerase III elongation complex 2 | electron microscopy | G | — | — |
| 7AST | Apo Human RNA Polymerase III | electron microscopy | J | — | 2 (best 0.79) |
| 7AST | Apo human RNA polymerase III | electron microscopy | J | — | — |
| 7D58 | cryo-EM structure of human RNA polymerase III in elongating state | electron microscopy | G | — | 1 (best 0.78) |
| 7D58 | Cryo-EM structure of human RNA polymerase III in elongating state | electron microscopy | G | — | — |
| 7D59 | cryo-EM structure of human RNA polymerase III in apo state | electron microscopy | G | — | 1 (best 0.81) |
| 7D59 | Cryo-EM structure of human RNA polymerase III in apo state | electron microscopy | G | — | — |
| 7DN3 | Structure of Human RNA Polymerase III elongation complex | electron microscopy | G | — | 2 (best 0.77) |
| 7DN3 | Structure of human RNA polymerase III elongation complex | electron microscopy | G | — | — |
| 7DU2 | RNA polymerase III EC complex in post-translocation state | electron microscopy | G | — | 2 (best 0.78) |
| 7DU2 | RNA polymerase III ec complex in post-translocation state | electron microscopy | G | — | — |
| 7FJI | human Pol III elongation complex | electron microscopy | G | — | 1 (best 0.73) |
| 7FJI | Human pol III elongation complex | electron microscopy | G | — | — |
| 7FJJ | human Pol III pre-termination complex | electron microscopy | G | — | 2 (best 0.75) |
| 7FJJ | Human pol III pre-termination complex | electron microscopy | G | — | — |
| 8ITY | human RNA polymerase III pre-initiation complex closed DNA 1 | electron microscopy | G | — | 1 (best 0.78) |
| 8IUE | RNA polymerase III pre-initiation complex melting complex 1 | electron microscopy | G | — | 2 (best 0.77) |
| 8IUH | RNA polymerase III pre-initiation complex open complex 1 | electron microscopy | G | — | 2 (best 0.77) |
| Q9Y535 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase III subunit RPC8 (Q9Y535) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 2 records
Experiment against prediction
- 7A6H chain G against the predicted model Q9Y535: TM-score 0.92, RMSD 1.76 Å
- 7A6H chain G against the predicted model Q9Y535: TM-score 0.92, RMSD 1.76 Å
- 7AE3 chain G against the predicted model Q9Y535: TM-score 0.92, RMSD 1.76 Å
- 7AE3 chain G against the predicted model Q9Y535: TM-score 0.92, RMSD 1.76 Å
- 7AE1 chain G against the predicted model Q9Y535: TM-score 0.91, RMSD 1.77 Å
- 7AE1 chain G against the predicted model Q9Y535: TM-score 0.91, RMSD 1.77 Å
- 7DN3 chain G against the predicted model Q9Y535: TM-score 0.91, RMSD 1.70 Å
- 7DN3 chain G against the predicted model Q9Y535: TM-score 0.91, RMSD 1.70 Å
- 7DU2 chain G against the predicted model Q9Y535: TM-score 0.91, RMSD 1.70 Å
- 7DU2 chain G against the predicted model Q9Y535: TM-score 0.91, RMSD 1.70 Å
Elsewhere
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