UniProt Q9Y4W6
AFG3-like protein 2 (Q9Y4W6)
AFG3-like protein 2 (UniProt Q9Y4W6), EC 3.4.24.-: 4 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y4W6
- Protein
- AFG3-like protein 2
- EC
- 3.4.24.-
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 20 · 1 record with a druggable one
Structures
5 records of Q9Y4W6 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2LNA | Solution NMR Structure of the mitochondrial inner membrane domain (residues 164-251), FtsH_ext… | solution nmr | A | — | — |
| 2LNA | Solution NMR structure of the mitochondrial inner membrane domain (residues 164-251), FTSH_EXT… | solution nmr | A | — | — |
| 6NYY | human m-AAA protease AFG3L2, substrate-bound | electron microscopy | A, B, C, D, E, F | ZN, ANP, MG, ADP | 20 (best 0.88) |
| 6NYY | Human M-aaa protease AFG3L2, substrate-bound | electron microscopy | A, B, C, D, E, F | ZN, ANP, MG, ADP | — |
| Q9Y4W6 | AlphaFold monomer V2.0 prediction for AFG3-like protein 2 (Q9Y4W6) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6NYY chain D against the predicted model Q9Y4W6: TM-score 0.98, RMSD 1.23 Å
- 6NYY chain D against the predicted model Q9Y4W6: TM-score 0.98, RMSD 1.23 Å
- 6NYY chain C against the predicted model Q9Y4W6: TM-score 0.97, RMSD 1.48 Å
- 6NYY chain C against the predicted model Q9Y4W6: TM-score 0.97, RMSD 1.48 Å
- 6NYY chain B against the predicted model Q9Y4W6: TM-score 0.93, RMSD 2.20 Å
- 6NYY chain B against the predicted model Q9Y4W6: TM-score 0.93, RMSD 2.20 Å
- 6NYY chain E against the predicted model Q9Y4W6: TM-score 0.93, RMSD 2.23 Å
- 6NYY chain E against the predicted model Q9Y4W6: TM-score 0.93, RMSD 2.23 Å
- 6NYY chain F against the predicted model Q9Y4W6: TM-score 0.82, RMSD 3.80 Å
- 6NYY chain F against the predicted model Q9Y4W6: TM-score 0.82, RMSD 3.80 Å
Elsewhere
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