UniProt Q9Y4R8
Telomere length regulation protein TEL2 homolog (Q9Y4R8)
Telomere length regulation protein TEL2 homolog (UniProt Q9Y4R8): 6 experimental structures and 1 predicted model on GenesisL1, 35 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y4R8
- Protein
- Telomere length regulation protein TEL2 homolog
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 35 · 5 records with a druggable one
Structures
7 records of Q9Y4R8 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4PSI | PIH1D1/phospho-Tel2 complex | x-ray diffraction | D, E | — | — |
| 4PSI | PIH1D1/PHOSPHO-TEL2 complex | x-ray diffraction | D, E | — | — |
| 7F4U | Cryo-EM structure of TELO2-TTI1-TTI2 complex | electron microscopy | A | — | 13 (best 0.82) |
| 7F4U | Cryo-EM structure of TELO2-TTI1-TTI2 complex | electron microscopy | A | — | 13 (best 0.82) |
| 7OLE | Cryo-EM structure of the TELO2-TTI1-TTI2-RUVBL1-RUVBL2 complex | electron microscopy | K | — | 2 (best 0.75) |
| 7OLE | Cryo-EM structure of the TELO2-TTI1-TTI2-RUVBL1-RUVBL2 complex | electron microscopy | K | — | 2 (best 0.75) |
| Q9Y4R8 | AlphaFold monomer V2.0 prediction for telomere length regulation protein TEL2 homolog (Q9Y4R8) | predicted | A | — | 5 (best 0.59) |
Experiment against prediction
- 7OLE chain K against the predicted model Q9Y4R8: TM-score 0.85, RMSD 2.92 Å
- 7OLE chain K against the predicted model Q9Y4R8: TM-score 0.85, RMSD 2.92 Å
- 7F4U chain A against the predicted model Q9Y4R8: TM-score 0.84, RMSD 3.00 Å
- 7F4U chain A against the predicted model Q9Y4R8: TM-score 0.84, RMSD 3.00 Å
- 4PSI chain E against the predicted model Q9Y4R8: TM-score 0.45, RMSD 1.23 Å
- 4PSI chain E against the predicted model Q9Y4R8: TM-score 0.45, RMSD 1.23 Å
- 4PSI chain D against the predicted model Q9Y4R8: TM-score 0.41, RMSD 2.13 Å
- 4PSI chain D against the predicted model Q9Y4R8: TM-score 0.41, RMSD 2.13 Å
Elsewhere
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