UniProt Q9Y490
Talin-1 (Q9Y490)
Talin-1 (UniProt Q9Y490): 8 experimental structures and 1 predicted model on GenesisL1, 40 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y490
- Protein
- Talin-1
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 40 · 2 records with a druggable one
Structures
9 records of Q9Y490 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1SYQ | Human vinculin head domain VH1, residues 1-258, in complex with human talin's vinculin binding site… | x-ray diffraction | B | — | — |
| 1SYQ | Human vinculin head domain VH1, residues 1-258, in complex with human TALIN'S vinculin binding site… | x-ray diffraction | B | — | — |
| 2MWN | Talin-F3 / RIAM N-terminal Peptide complex | solution nmr | B | — | — |
| 2MWN | Talin-F3 / riam N-terminal peptide complex | solution nmr | B | — | — |
| 4DJ9 | Human vinculin head domain Vh1 (residues 1-258) in complex with the talin vinculin binding site 50… | x-ray diffraction | B | — | — |
| 4DJ9 | Human vinculin head domain VH1 (residues 1-258) in complex with the talin vinculin binding site 50… | x-ray diffraction | B | — | — |
| 6R9T | Cryo-EM structure of autoinhibited human talin-1 | electron microscopy | A | — | 20 (best 0.82) |
| 6R9T | Cryo-EM structure of autoinhibited human talin-1 | electron microscopy | A | — | — |
| Q9Y490 | AlphaFold monomer V2.0 prediction for talin-1 (Q9Y490) | predicted | A | — | 20 (best 0.80) |
Experiment against prediction
- 2MWN chain B against the predicted model Q9Y490: TM-score 0.87, RMSD 1.60 Å
- 2MWN chain B against the predicted model Q9Y490: TM-score 0.87, RMSD 1.60 Å
- 4DJ9 chain B against the predicted model Q9Y490: TM-score 0.83, RMSD 0.37 Å
- 4DJ9 chain B against the predicted model Q9Y490: TM-score 0.83, RMSD 0.37 Å
- 1SYQ chain B against the predicted model Q9Y490: TM-score 0.76, RMSD 1.25 Å
- 1SYQ chain B against the predicted model Q9Y490: TM-score 0.76, RMSD 1.25 Å
- 6R9T chain A against the predicted model Q9Y490: TM-score 0.65, RMSD 6.40 Å
- 6R9T chain A against the predicted model Q9Y490: TM-score 0.65, RMSD 6.40 Å
Elsewhere
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