UniProt Q9Y2Y1
DNA-directed RNA polymerase III subunit RPC10 (Q9Y2Y1)
DNA-directed RNA polymerase III subunit RPC10 (UniProt Q9Y2Y1): 20 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 19 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q9Y2Y1
- Protein
- DNA-directed RNA polymerase III subunit RPC10
- Experimental structures
- 20
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 19 · 9 records with a druggable one
Structures
21 records of Q9Y2Y1 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7A6H | Cryo-EM structure of human apo RNA polymerase III | electron microscopy | I | ZN | — |
| 7AE1 | Cryo-EM structure of human RNA Polymerase III elongation complex 1 | electron microscopy | I | ZN | 1 (best 0.72) |
| 7AE1 | Cryo-EM structure of human RNA polymerase III elongation complex 1 | electron microscopy | I | ZN | — |
| 7AE3 | Cryo-EM structure of human RNA Polymerase III elongation complex 3 | electron microscopy | I | ZN | 3 (best 0.84) |
| 7AE3 | Cryo-EM structure of human RNA polymerase III elongation complex 3 | electron microscopy | I | ZN | — |
| 7AEA | Cryo-EM structure of human RNA Polymerase III elongation complex 2 | electron microscopy | I | ZN | 2 (best 0.69) |
| 7AEA | Cryo-EM structure of human RNA polymerase III elongation complex 2 | electron microscopy | I | ZN | — |
| 7AST | Apo human RNA polymerase III | electron microscopy | A | — | — |
| 7D58 | cryo-EM structure of human RNA polymerase III in elongating state | electron microscopy | I | ZN | 3 (best 0.87) |
| 7D58 | Cryo-EM structure of human RNA polymerase III in elongating state | electron microscopy | I | ZN | — |
| 7D59 | cryo-EM structure of human RNA polymerase III in apo state | electron microscopy | I | ZN | 2 (best 0.86) |
| 7D59 | Cryo-EM structure of human RNA polymerase III in apo state | electron microscopy | I | ZN | — |
| 7DN3 | Structure of human RNA polymerase III elongation complex | electron microscopy | I | ZN | — |
| 7DU2 | RNA polymerase III ec complex in post-translocation state | electron microscopy | I | ZN | — |
| 7FJI | human Pol III elongation complex | electron microscopy | I | ZN | 4 (best 0.86) |
| 7FJI | Human pol III elongation complex | electron microscopy | I | ZN | — |
| 7FJJ | human Pol III pre-termination complex | electron microscopy | I | ZN | 1 (best 0.70) |
| 7FJJ | Human pol III pre-termination complex | electron microscopy | I | ZN | — |
| 8ITY | human RNA polymerase III pre-initiation complex closed DNA 1 | electron microscopy | I | ZN | 1 (best 0.81) |
| 8IUE | RNA polymerase III pre-initiation complex melting complex 1 | electron microscopy | I | ZN | 2 (best 0.84) |
| Q9Y2Y1 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase III subunit RPC10 (Q9Y2Y1) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 19 records
Experiment against prediction
- 8ITY chain I against the predicted model Q9Y2Y1: TM-score 0.71, RMSD 1.11 Å
- 7DU2 chain I against the predicted model Q9Y2Y1: TM-score 0.70, RMSD 1.48 Å
- 7DN3 chain I against the predicted model Q9Y2Y1: TM-score 0.59, RMSD 1.50 Å
- 7AST chain A against the predicted model Q9Y2Y1: TM-score 0.51, RMSD 2.50 Å
- 7FJI chain I against the predicted model Q9Y2Y1: TM-score 0.42, RMSD 2.48 Å
- 7FJI chain I against the predicted model Q9Y2Y1: TM-score 0.42, RMSD 2.48 Å
- 7AE3 chain I against the predicted model Q9Y2Y1: TM-score 0.42, RMSD 2.46 Å
- 7AE3 chain I against the predicted model Q9Y2Y1: TM-score 0.42, RMSD 2.46 Å
- 8IUE chain I against the predicted model Q9Y2Y1: TM-score 0.42, RMSD 2.42 Å
- 7A6H chain I against the predicted model Q9Y2Y1: TM-score 0.39, RMSD 1.71 Å
Elsewhere
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