UniProt Q9Y2T5
Chimera of G-protein coupled receptor 52 and Flavodoxin (Q9Y2T5)
Chimera of G-protein coupled receptor 52 and Flavodoxin (UniProt Q9Y2T5): 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 23 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9Y2T5
- Protein
- Chimera of G-protein coupled receptor 52 and Flavodoxin
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 23 · 4 records with a druggable one
Structures
9 records of Q9Y2T5 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6LI0 | Crystal structure of GPR52 in complex with agonist c17 | x-ray diffraction | A | EN6, FMN | 5 (best 0.79) |
| 6LI0 | Crystal structure of GPR52 in complex with agonist C17 | x-ray diffraction | A | EN6, FMN | — |
| 6LI1 | Crystal structure of GPR52 ligand free form with flavodoxin fusion | x-ray diffraction | A | FMN | 5 (best 0.80) |
| 6LI1 | Crystal structure of GPR52 ligand free form with flavodoxin fusion | x-ray diffraction | A | FMN | — |
| 6LI2 | Crystal structure of GPR52 ligand free form with rubredoxin fusion | x-ray diffraction | A | ZN | 2 (best 0.55) |
| 6LI2 | Crystal structure of GPR52 ligand free form with rubredoxin fusion | x-ray diffraction | A | ZN | — |
| 6LI3 | Cryo-EM structure of GPR52-minigs-NB35 | electron microscopy | R | — | — |
| 8HMP | GPR52 with Gs and c17 | electron microscopy | R | EN6 | 7 (best 0.78) |
| Q9Y2T5 | AlphaFold monomer V2.0 prediction for G-protein coupled receptor 52 (Q9Y2T5) | predicted | A | — | 4 (best 0.50) |
Ligands
Experiment against prediction
- 6LI1 chain A against the predicted model P00323: TM-score 0.33, RMSD 0.40 Å
- 6LI1 chain A against the predicted model P00323: TM-score 0.33, RMSD 0.40 Å
- 6LI0 chain A against the predicted model P00323: TM-score 0.33, RMSD 0.65 Å
- 6LI0 chain A against the predicted model P00323: TM-score 0.33, RMSD 0.65 Å
- 6LI2 chain A against the predicted model P00268: TM-score 0.16, RMSD 0.38 Å
- 6LI2 chain A against the predicted model P00268: TM-score 0.16, RMSD 0.38 Å
- 6LI3 chain R against the predicted model Q9Y2T5: TM-score 0.92, RMSD 2.11 Å
- 8HMP chain R against the predicted model Q9Y2T5: TM-score 0.92, RMSD 2.10 Å
- 6LI1 chain A against the predicted model Q9Y2T5: TM-score 0.67, RMSD 2.33 Å
- 6LI1 chain A against the predicted model Q9Y2T5: TM-score 0.67, RMSD 2.33 Å
Elsewhere
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