UniProt Q9Y248
DNA replication complex GINS protein PSF2 (Q9Y248)
DNA replication complex GINS protein PSF2 (UniProt Q9Y248): 12 experimental structures and 1 predicted model on GenesisL1, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y248
- Protein
- DNA replication complex GINS protein PSF2
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 15 · 4 records with a druggable one
Structures
13 records of Q9Y248 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2E9X | The crystal structure of human GINS core complex | x-ray diffraction | B, F | — | — |
| 2E9X | The crystal structure of human gins core complex | x-ray diffraction | B, F | — | — |
| 2EHO | Crystal structure of human GINS complex | x-ray diffraction | C, G, K | — | — |
| 2EHO | Crystal structure of human gins complex | x-ray diffraction | C, G, K | — | — |
| 2Q9Q | The crystal structure of full length human GINS complex | x-ray diffraction | A, E | — | — |
| 2Q9Q | The crystal structure of full length human gins complex | x-ray diffraction | A, E | — | — |
| 6XTX | CryoEM structure of human CMG bound to ATPgammaS and DNA | electron microscopy | B | — | 2 (best 0.87) |
| 6XTX | Cryoem structure of human cmg bound to atpgammas and DNA | electron microscopy | B | — | — |
| 6XTY | Cryoem structure of human cmg bound to and-1 (cmga) | electron microscopy | B | — | — |
| 7PFO | Core human replisome | electron microscopy | E | — | 4 (best 0.89) |
| 7PLO | H. sapiens replisome-CUL2/LRR1 complex | electron microscopy | E | — | 2 (best 0.90) |
| 8OK2 | Bipartite interaction of TOPBP1 with the GINS complex | electron microscopy | B | — | 6 (best 0.86) |
| Q9Y248 | AlphaFold monomer V2.0 prediction for DNA replication complex gins protein PSF2 (Q9Y248) | predicted | A | — | 1 (best 0.40) |
Experiment against prediction
- 2EHO chain K against the predicted model Q9Y248: TM-score 0.97, RMSD 0.81 Å
- 2EHO chain K against the predicted model Q9Y248: TM-score 0.97, RMSD 0.81 Å
- 8OK2 chain B against the predicted model Q9Y248: TM-score 0.97, RMSD 0.94 Å
- 2E9X chain B against the predicted model Q9Y248: TM-score 0.97, RMSD 1.01 Å
- 2E9X chain B against the predicted model Q9Y248: TM-score 0.97, RMSD 1.01 Å
- 2EHO chain C against the predicted model Q9Y248: TM-score 0.97, RMSD 0.85 Å
- 2EHO chain C against the predicted model Q9Y248: TM-score 0.97, RMSD 0.85 Å
- 2Q9Q chain A against the predicted model Q9Y248: TM-score 0.96, RMSD 1.13 Å
- 2Q9Q chain A against the predicted model Q9Y248: TM-score 0.96, RMSD 1.13 Å
- 6XTY chain B against the predicted model Q9Y248: TM-score 0.95, RMSD 1.18 Å
Elsewhere
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