UniProt Q9UTG2
E3 ubiquitin-protein ligase pub2 (Q9UTG2)
E3 ubiquitin-protein ligase pub2 (UniProt Q9UTG2), EC 2.3.2.26: 3 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q9UTG2
- Protein
- E3 ubiquitin-protein ligase pub2
- EC
- 2.3.2.26
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 18 · 4 records with a druggable one
Structures
4 records of Q9UTG2 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 9B56 | Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 2 | electron microscopy | C | A1AIV | 6 (best 0.77) |
| 9B59 | Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 5 | electron microscopy | C | A1AIV | 4 (best 0.80) |
| 9B5A | Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 6 | electron microscopy | C | A1AIV | 4 (best 0.80) |
| Q9UTG2 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase PUB2 (Q9UTG2) | predicted | A | — | 4 (best 0.70) |
Ligands
- A1AIV · 4-aminobutanenitrile · in 3 records
Experiment against prediction
- 9B59 chain C against the predicted model Q9UTG2: TM-score 0.70, RMSD 2.15 Å
- 9B56 chain C against the predicted model Q9UTG2: TM-score 0.70, RMSD 2.32 Å
- 9B5A chain C against the predicted model Q9UTG2: TM-score 0.70, RMSD 2.16 Å
Elsewhere
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