UniProt Q9UPN9
E3 ubiquitin-protein ligase TRIM33 (Q9UPN9)
E3 ubiquitin-protein ligase TRIM33 (UniProt Q9UPN9): 10 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UPN9
- Protein
- E3 ubiquitin-protein ligase TRIM33
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
11 records of Q9UPN9 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3U5M | Crystal structure of TRIM33 PHD-Bromo in the free state | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 3U5M | Crystal structure of TRIM33 phd-bromo in the free state | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 3U5N | Crystal structure of the complex of TRIM33 PHD-Bromo and H3(1-20)K9me3K14ac histone peptide | x-ray diffraction | A, B | — | — |
| 3U5N | Crystal structure of the complex of TRIM33 phd-bromo and H3(1-20) K9ME3K14AC histone peptide | x-ray diffraction | A, B | — | — |
| 3U5O | Crystal structure of the complex of TRIM33 PHD-Bromo and H3(1-22)K9me3K14acK18ac histone peptide | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 3U5O | Crystal structure of the complex of TRIM33 phd-bromo and H3(1-22) K9ME3K14ACK18AC histone peptide | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 3U5P | Crystal structure of the complex of TRIM33 PHD-Bromo and H3(1-28)K9me3K14acK18acK23ac histone… | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 3U5P | Crystal structure of the complex of TRIM33 phd-bromo and H3(1-28) K9ME3K14ACK18ACK23AC histone… | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 5MR8 | Crystal structure of TRIM33 phd-bromodomain isoform B in complex with H3K9AC histone peptide | x-ray diffraction | A | ZN | — |
| 7ZDD | Crystal structure of TRIM33 phd-bromodomain isoform B in complex with H3K10AC histone peptide. | x-ray diffraction | A | ZN | — |
| Q9UPN9 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase TRIM33 (Q9UPN9) | predicted | A | — | 6 (best 0.53) |
Ligands
- ZN · Zinc ion · in 2 records
Experiment against prediction
- 3U5N chain B against the predicted model Q9UPN9: TM-score 0.98, RMSD 0.67 Å
- 3U5N chain B against the predicted model Q9UPN9: TM-score 0.98, RMSD 0.67 Å
- 7ZDD chain A against the predicted model Q9UPN9: TM-score 0.98, RMSD 0.93 Å
- 3U5M chain A against the predicted model Q9UPN9: TM-score 0.98, RMSD 0.79 Å
- 3U5M chain A against the predicted model Q9UPN9: TM-score 0.98, RMSD 0.79 Å
- 3U5M chain E against the predicted model Q9UPN9: TM-score 0.98, RMSD 0.80 Å
- 3U5M chain E against the predicted model Q9UPN9: TM-score 0.98, RMSD 0.80 Å
- 3U5N chain A against the predicted model Q9UPN9: TM-score 0.97, RMSD 1.01 Å
- 3U5N chain A against the predicted model Q9UPN9: TM-score 0.97, RMSD 1.01 Å
- 3U5M chain D against the predicted model Q9UPN9: TM-score 0.97, RMSD 0.83 Å
Elsewhere
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