UniProt Q9UL46
Proteasome activator complex subunit 2 (Q9UL46)
Proteasome activator complex subunit 2 (UniProt Q9UL46): 7 experimental structures and 1 predicted model on GenesisL1, 48 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UL46
- Protein
- Proteasome activator complex subunit 2
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 48 · 5 records with a druggable one
Structures
8 records of Q9UL46 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7DR6 | PA28alpha-beta in complex with immunoproteasome | electron microscopy | A, D, F | — | 8 (best 0.84) |
| 7DR6 | PA28ALPHA-beta in complex with immunoproteasome | electron microscopy | A, D, F | — | — |
| 7DRW | Bovine 20S immunoproteasome in complex with two human PA28alpha-beta activators | electron microscopy | H, K, M, O, c, g | — | 12 (best 0.86) |
| 7DRW | Bovine 20S immunoproteasome in complex with two human PA28ALPHA-beta activators | electron microscopy | H, K, M, O, c, g | — | — |
| 7NAO | Human PA28-20S proteasome complex | electron microscopy | d, f, h, i | — | 8 (best 0.81) |
| 7NAP | Human PA28-20S-PA28 proteasome complex | electron microscopy | k, m, o, p, d, f, h, i | — | 13 (best 0.81) |
| 8CXB | Human PA28-20S (PA28-4a3b) | electron microscopy | c, e, g | — | 7 (best 0.82) |
| Q9UL46 | AlphaFold monomer V2.0 prediction for proteasome activator complex subunit 2 (Q9UL46) | predicted | A | — | — |
Experiment against prediction
- 7NAO chain f against the predicted model Q9UL46: TM-score 0.99, RMSD 0.64 Å
- 7NAP chain m against the predicted model Q9UL46: TM-score 0.99, RMSD 0.64 Å
- 7NAO chain d against the predicted model Q9UL46: TM-score 0.96, RMSD 0.66 Å
- 7NAP chain k against the predicted model Q9UL46: TM-score 0.96, RMSD 0.66 Å
- 7NAP chain o against the predicted model Q9UL46: TM-score 0.96, RMSD 0.72 Å
- 7NAO chain h against the predicted model Q9UL46: TM-score 0.96, RMSD 0.72 Å
- 7DR6 chain A against the predicted model Q9UL46: TM-score 0.95, RMSD 1.15 Å
- 7DR6 chain A against the predicted model Q9UL46: TM-score 0.95, RMSD 1.15 Å
- 8CXB chain c against the predicted model Q9UL46: TM-score 0.94, RMSD 1.28 Å
- 7DRW chain H against the predicted model Q9UL46: TM-score 0.94, RMSD 1.40 Å
Elsewhere
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