UniProt Q9UKK3

Protein mono-ADP-ribosyltransferase PARP4 (Q9UKK3)

Protein mono-ADP-ribosyltransferase PARP4 (UniProt Q9UKK3), EC 2.4.2.-: 4 experimental structures on GenesisL1, 2 ligands bound, 36 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt: Q9UKK3
Protein: Protein mono-ADP-ribosyltransferase PARP4
EC: 2.4.2.-
Experimental structures: 4
Predicted models: 0
Ligands: 2
Pockets: 36 · 3 records with a druggable one

Structures

4 records of Q9UKK3 in the MolNFT archive: 4 experimental, 0 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
8SWY	PARP4 ART domain bound to NADH	x-ray diffraction	A, B, C	NAI	7 (best 0.71)
8SWZ	PARP4 ART domain bound to EB47	x-ray diffraction	A, B, C	UHB	9 (best 0.70)
8SX1	PARP4 catalytic domain	x-ray diffraction	A, B, C, D, E, F, G, H	—	20 (best 0.81)
Q9UKK3	AlphaFold monomer V2.0 prediction for protein mono-ADP- ribosyltransferase PARP4 (Q9UKK3)	—		—	—

Ligands

NAI · 1,4-dihydronicotinamide adenine dinucleotide · in 1 record
UHB · 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide · in 1 record

Elsewhere

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