UniProt Q9UK17
Isoform 2 of Potassium voltage-gated channel subfamily D member 3 (Q9UK17)
Isoform 2 of Potassium voltage-gated channel subfamily D member 3 (UniProt Q9UK17): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 89 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q9UK17
- Protein
- Isoform 2 of Potassium voltage-gated channel subfamily D member 3
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 89 · 6 records with a druggable one
Structures
9 records of Q9UK17 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1S1G | Crystal Structure of Kv4.3 T1 Domain | x-ray diffraction | A, B | ZN | 1 (best 0.49) |
| 1S1G | Crystal structure of KV4.3 T1 domain | x-ray diffraction | A, B | ZN | 1 (best 0.49) |
| 2NZ0 | Crystal structure of potassium channel Kv4.3 in complex with its regulatory subunit KChIP1 | x-ray diffraction | B, D | ZN | 8 (best 0.74) |
| 2NZ0 | Crystal structure of potassium channel KV4.3 in complex with its regulatory subunit KCHIP1 (casp… | x-ray diffraction | B, D | ZN | 8 (best 0.74) |
| 7W3Y | CryoEM structure of human Kv4.3 | electron microscopy | A, B, C, D | — | 20 (best 0.80) |
| 7W6N | CryoEM structure of human KChIP1-Kv4.3 complex | electron microscopy | B, D, F, H | — | 20 (best 0.81) |
| 7W6S | CryoEM structure of human KChIP2-Kv4.3 complex | electron microscopy | B, D, F, H | — | 20 (best 0.83) |
| 7W6T | CryoEM structure of human KChIP1-Kv4.3-DPP6 complex | electron microscopy | B, D, F, H | — | 11 (best 0.85) |
| Q9UK17 | AlphaFold monomer V2.0 prediction for potassium voltage-gated channel subfamily D member 3 (Q9UK17) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 4 records
Experiment against prediction
- 1S1G chain B against the predicted model Q9UK17: TM-score 0.98, RMSD 0.55 Å
- 1S1G chain B against the predicted model Q9UK17: TM-score 0.98, RMSD 0.55 Å
- 1S1G chain A against the predicted model Q9UK17: TM-score 0.97, RMSD 0.68 Å
- 1S1G chain A against the predicted model Q9UK17: TM-score 0.97, RMSD 0.68 Å
- 7W3Y chain A against the predicted model Q9UK17: TM-score 0.90, RMSD 2.52 Å
- 7W3Y chain B against the predicted model Q9UK17: TM-score 0.90, RMSD 2.52 Å
- 7W3Y chain C against the predicted model Q9UK17: TM-score 0.90, RMSD 2.52 Å
- 7W3Y chain D against the predicted model Q9UK17: TM-score 0.90, RMSD 2.52 Å
- 7W6T chain H against the predicted model Q9UK17: TM-score 0.81, RMSD 2.91 Å
- 7W6T chain B against the predicted model Q9UK17: TM-score 0.81, RMSD 2.81 Å
Elsewhere
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