UniProt Q9UIF8
Bromodomain adjacent to zinc finger domain protein 2B (Q9UIF8)
Bromodomain adjacent to zinc finger domain protein 2B (UniProt Q9UIF8): 490 experimental structures and 1 predicted model on GenesisL1, 50 ligands bound, 107 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9UIF8
- Protein
- Bromodomain adjacent to zinc finger domain protein 2B
- Experimental structures
- 490
- Predicted models
- 1
- Ligands
- 50
- Pockets
- 107 · 2 records with a druggable one
Structures
491 records of Q9UIF8 in the MolNFT archive: 490 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2E7O | Solution structure of the Bromodomain from human Bromodomain adjacent to zinc finger domain 2B | solution nmr | A | — | — |
| 2E7O | Solution structure of the bromodomain from human bromodomain adjacent to zinc finger domain 2B | solution nmr | A | — | — |
| 3G0L | Crystal Structure of Human Bromodomain Adjacent to Zinc finger domain 2B (BAZ2B) | x-ray diffraction | A | — | — |
| 3G0L | Crystal structure of human bromodomain adjacent to zinc finger domain 2B (BAZ2B) | x-ray diffraction | A | — | — |
| 3Q2F | Crystal Structure of the bromodomain of human BAZ2B in complex with a triazolo ligand | x-ray diffraction | A | — | — |
| 3Q2F | Crystal structure of the bromodomain of human BAZ2B in complex with a triazolo ligand | x-ray diffraction | A | — | — |
| 4CUP | Crystal structure of human BAZ2B in complex with fragment-1 N09421 | x-ray diffraction | A | — | — |
| 4CUP | Crystal structure of human BAZ2B in complex with fragment-1 N09421 | x-ray diffraction | A | — | — |
| 4CUQ | Crystal structure of human BAZ2B in complex with fragment-2 N09594 | x-ray diffraction | A | — | — |
| 4CUQ | Crystal structure of human BAZ2B in complex with fragment-2 N09594 | x-ray diffraction | A | — | — |
| 4CUR | Crystal structure of human BAZ2B in complex with fragment-3 N09555 | x-ray diffraction | A | — | — |
| 4CUR | Crystal structure of human BAZ2B in complex with fragment-3 N09555 | x-ray diffraction | A | — | — |
| 4CUS | Crystal structure of human BAZ2B in complex with fragment-4 N09496 | x-ray diffraction | A | — | — |
| 4CUS | Crystal structure of human BAZ2B in complex with fragment-4 N09496 | x-ray diffraction | A | — | — |
| 4CUT | Crystal structure of human BAZ2B in complex with fragment-5 N09428 | x-ray diffraction | A | — | — |
| 4CUT | Crystal structure of human BAZ2B in complex with fragment-5 N09428 | x-ray diffraction | A | — | — |
| 4CUU | Crystal structure of human BAZ2B in complex with fragment-6 N09645 | x-ray diffraction | A | — | — |
| 4CUU | Crystal structure of human BAZ2B in complex with fragment-6 N09645 | x-ray diffraction | A | — | — |
| 4IR3 | Crystal Structure of the bromodomain of human BAZ2B in complex with… | x-ray diffraction | A | — | — |
| 4IR3 | Crystal structure of the bromodomain of human BAZ2B in complex with 1… | x-ray diffraction | A | — | — |
| 4IR4 | Crystal Structure of the bromodomain of human BAZ2B in complex with… | x-ray diffraction | A | — | — |
| 4IR4 | Crystal structure of the bromodomain of human BAZ2B in complex with 1… | x-ray diffraction | A | — | — |
| 4IR5 | Crystal Structure of the bromodomain of human BAZ2B in complex with… | x-ray diffraction | A | — | — |
| 4IR5 | Crystal structure of the bromodomain of human BAZ2B in complex with 1… | x-ray diffraction | A | — | — |
| 4IR6 | Crystal Structure of the bromodomain of human BAZ2B in complex with… | x-ray diffraction | A | — | — |
| 4IR6 | Crystal structure of the bromodomain of human BAZ2B in complex with 1… | x-ray diffraction | A | — | — |
| 4NR9 | Crystal Structure of the bromodomain of human BAZ2B in complex with acetylated lysine | x-ray diffraction | A | — | — |
| 4NR9 | Crystal structure of the bromodomain of human BAZ2B in complex with acetylated lysine | x-ray diffraction | A | — | — |
| 4NRA | Crystal Structure of the bromodomain of human BAZ2B in complex with compound-6 E11322 | x-ray diffraction | A | — | — |
| 4NRA | Crystal structure of the bromodomain of human BAZ2B in complex with compound-6 E11322 | x-ray diffraction | A | — | — |
| 4NRB | Crystal Structure of the bromodomain of human BAZ2B in complex with compound-1 N01197 | x-ray diffraction | A | — | — |
| 4NRB | Crystal structure of the bromodomain of human BAZ2B in complex with compound-1 N01197 | x-ray diffraction | A | — | — |
| 4NRC | Crystal Structure of the bromodomain of human BAZ2B in complex with compound-3 N01186 | x-ray diffraction | A | — | — |
| 4NRC | Crystal structure of the bromodomain of human BAZ2B in complex with compound-3 N01186 | x-ray diffraction | A | — | — |
| 4QC1 | Crystal structure of human BAZ2B bromodomain in complex with an acetylated histone 3 peptide… | x-ray diffraction | A, B | — | — |
| 4QC1 | Crystal structure of human BAZ2B bromodomain in complex with an acetylated histone 3 peptide… | x-ray diffraction | A, B | — | — |
| 4QC3 | Crystal structure of human BAZ2B bromodomain in complex with a diacetylated histone 4 peptide… | x-ray diffraction | A, B | — | — |
| 4QC3 | Crystal structure of human BAZ2B bromodomain in complex with a diacetylated histone 4 peptide… | x-ray diffraction | A, B | — | — |
| 4QF3 | Crystal structure of human BAZ2B PHD zinc finger in the free form | x-ray diffraction | A, B | — | — |
| 4QF3 | Crystal structure of human BAZ2B phd zinc finger in the free form | x-ray diffraction | A, B | — | — |
| 4RVR | Crystal Structure of the bromodomain of human BAZ2B in complex WITH GSK2801 | x-ray diffraction | A | — | — |
| 4RVR | Crystal structure of the bromodomain of human BAZ2B in complex with GSK2801 | x-ray diffraction | A | — | — |
| 4XUA | Crystal Structure of the bromodomain of human BAZ2B in complex with E11919 BAZ2-ICR analogue | x-ray diffraction | A | 43C | 1 (best 0.49) |
| 4XUA | Crystal structure of the bromodomain of human BAZ2B in complex with E11919 BAZ2-icr analogue | x-ray diffraction | A | — | — |
| 4XUB | Crystal Structure of the bromodomain of human BAZ2B in complex with BAZ2-ICR chemical probe | x-ray diffraction | A | 43D | 1 (best 0.45) |
| 4XUB | Crystal structure of the bromodomain of human BAZ2B in complex with BAZ2-icr chemical probe | x-ray diffraction | A | — | — |
| 5CQ3 | Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B… | x-ray diffraction | A | 53B, PO4 | 1 (best 0.46) |
| 5CQ3 | Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B… | x-ray diffraction | A | — | — |
| 5CQ4 | Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B… | x-ray diffraction | A | 53C, CL, SO4 | 1 (best 0.46) |
| 5CQ4 | Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B… | x-ray diffraction | A | — | — |
| 5CQ5 | Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B… | x-ray diffraction | A | 53E | — |
| 5CQ5 | Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B… | x-ray diffraction | A | — | — |
| 5CQ6 | Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B… | x-ray diffraction | A | PDC | 1 (best 0.44) |
| 5CQ6 | Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B… | x-ray diffraction | A | — | — |
| 5CQ7 | Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B… | x-ray diffraction | A | 53G | — |
| 5CQ7 | Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B… | x-ray diffraction | A | — | — |
| 5CQ8 | Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B… | x-ray diffraction | A | AC6 | — |
| 5CQ8 | Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B… | x-ray diffraction | A | — | — |
| 5CQA | Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B… | x-ray diffraction | A | 2LY | — |
| 5CQA | Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B… | x-ray diffraction | A | — | — |
431 records more on the page itself.
Ligands
- ZN · Zinc ion · in 4 records
- 53B · 6-hydroxypyridine-2-carboxylic acid · in 3 records
- AC6 · P-hydroxyacetophenone · in 3 records
- 53C · 1-(3-hydroxyphenyl)ethanone · in 2 records
- 6RR · ~{N}-[(3~{R})-1,1-bis(oxidanylidene)thian-3-yl]-2-methyl-pyridin-3-amine · in 2 records
- 6RS · ~{N}-[(1~{S})-1-(3,4-dihydro-2~{H}-1,5-benzodioxepin-7-yl)ethyl]-2-methyl-pyridin-3-amine · in 2 records
- 6RW · 2-methyl-~{N}-[(2~{S})-2-methylsulfonylcyclopentyl]pyridin-3-amine · in 2 records
- 6RY · ~{N}-[(1~{S})-1-(2,3-dihydro-1,4-benzodioxin-6-yl) ethyl]-2-methyl-pyridin-3-amine · in 2 records
- 6RZ · 2-methyl-~{N}-[(2~{R})-1-methylsulfonylpropan-2-yl]pyridin-3-amine · in 2 records
- 6S0 · 2-methyl-~{N}-[(1~{S})-1-thieno[3,2-b]pyridin-6-ylethyl]pyridin-3-amine · in 2 records
- 7MU · 4-chloranyl-~{N}-methyl-pyridine-2-carboxamide · in 2 records
- 7MW · methyl 4-propanoyl-1~{H}-pyrrole-2-carboxylate · in 2 records
- 7MX · ethyl 4-chloranyl-1-methyl-6-oxidanylidene-pyridine-3-carboxylate · in 2 records
- 8H4 · 1~{H}-indazol-5-amine · in 2 records
- 8HJ · 7-oxidanyl-3,4-dihydro-1~{H}-quinolin-2-one · in 2 records
- D3H · ~{N}-(4-aminophenyl)-2-azanyl-ethanamide · in 2 records
- D8Q · ~{N}-(2-azanylethyl)-1-methyl-6-oxidanylidene-pyridine-3-carboxamide · in 2 records
- D9Q · 1-methyl-6-oxidanylidene-~{N}-(2-pyrrolidin-1-ylethyl) pyridine-3-carboxamide · in 2 records
- D9T · ~{N}-[(1-azanylcyclohexyl)methyl]-1-methyl-6-oxidanylidene-pyridine-3-carboxamide · in 2 records
- DE5 · 2-azanyl-~{N}-(1,3-thiazol-2-yl)ethanamide · in 2 records
- EN2 · ~{N}-[3-[(4-fluorophenyl)carbonylamino]propyl]-1-methyl-6-oxidanylidene-pyridine-3-carboxamide · in 2 records
- ES3 · 4-bromo-1H-imidazole · in 2 records
- TYL · N-(4-hydroxyphenyl)acetamide (tylenol) · in 2 records
- TYZ · Para acetamido benzoic acid · in 2 records
- 2LY · N-methyl-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carboxamide · in 1 record
- 43C · 4-{1-[2-(4-methyl-1H-1,2,3-triazol-1-yl)ethyl]-4-phenyl-1H-imidazol-5-yl}benzonitrile · in 1 record
- 43D · 4-{4-(1-methyl-1H-pyrazol-4-yl)-1-[2-(4-methyl-1H-1,2,3-triazol-1-yl)ethyl]-1H-imidazol-5-yl}benzonitrile · in 1 record
- 53E · 2,3-dihydro-1,4-benzodioxine-5-carboxylic acid · in 1 record
- 53G · N,N-dimethylquinoxaline-6-carboxamide · in 1 record
- 54T · 6-chloro-1,3-benzothiazol-2-amine · in 1 record
Experiment against prediction
- 4QC1 chain B against the predicted model Q9UIF8: TM-score 0.97, RMSD 0.87 Å
- 4QC1 chain B against the predicted model Q9UIF8: TM-score 0.97, RMSD 0.87 Å
- 4QC3 chain B against the predicted model Q9UIF8: TM-score 0.96, RMSD 1.19 Å
- 4QC3 chain B against the predicted model Q9UIF8: TM-score 0.96, RMSD 1.19 Å
- 7WIN chain A against the predicted model Q9UIF8: TM-score 0.96, RMSD 0.78 Å
- 7WIN chain A against the predicted model Q9UIF8: TM-score 0.96, RMSD 0.78 Å
- 4QC1 chain A against the predicted model Q9UIF8: TM-score 0.96, RMSD 1.29 Å
- 4QC1 chain A against the predicted model Q9UIF8: TM-score 0.96, RMSD 1.29 Å
- 4QC3 chain A against the predicted model Q9UIF8: TM-score 0.96, RMSD 0.94 Å
- 4QC3 chain A against the predicted model Q9UIF8: TM-score 0.96, RMSD 0.94 Å
Elsewhere
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