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Ligand · IR4

IR4 · 1-[7-(morpholin-4-yl)-1-(pyridin-2-yl)indolizin-3-yl]ethanone

IR4, 1-[7-(morpholin-4-yl)-1-(pyridin-2-yl)indolizin-3-yl]ethanone (C19 H19 N3 O2, 321.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
IR4
Formula
C19 H19 N3 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

IR4 in 2 structures; the first of them:

  • 4IR4 · Crystal Structure of the bromodomain of human BAZ2B in complex with… · IR4 A2001 · binds TRP1887, PRO1888, PHE1889, VAL1893, LEU1897, VAL1898, TYR1901, PHE1943 and 2 more
  • 4IR4 · Crystal structure of the bromodomain of human BAZ2B in complex with 1… · IR4 A2001 · binds TRP1887, PRO1888, PHE1889, VAL1893, LEU1897, VAL1898, TYR1901, PHE1943 and 2 more

Residues it binds most

PHE 2, VAL 2, ASN 2, ILE 2, LEU 2, PRO 2, TRP 2, TYR 2 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

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