UniProt Q9UI32
Glutaminase liver isoform, mitochondrial (Q9UI32)
Glutaminase liver isoform, mitochondrial (UniProt Q9UI32), EC 3.5.1.2: 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 44 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9UI32
- Protein
- Glutaminase liver isoform, mitochondrial
- EC
- 3.5.1.2
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 44 · 2 records with a druggable one
Structures
7 records of Q9UI32 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4BQM | Crystal structure of human liver-type glutaminase, catalytic domain | x-ray diffraction | A, B | — | — |
| 4BQM | Crystal structure of human liver-type glutaminase, catalytic domain | x-ray diffraction | A, B | — | — |
| 5U0K | C-terminal ankyrin repeats from human liver-type glutaminase (GAB/LGA) | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | 4 (best 0.47) |
| 5U0K | C-terminal ankyrin repeats from human liver-type glutaminase (GAB/LGA) | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 8SZL | Human liver-type glutaminase (Apo form) | electron microscopy | A, B, C, D | — | 20 (best 0.87) |
| 8T0Z | Human liver-type glutaminase (K253A) with L-Gln, filamentous form | electron microscopy | A, B, C, D, E, G, I, K, F, H, J, L | GLN | 20 (best 0.78) |
| Q9UI32 | AlphaFold monomer V2.0 prediction for glutaminase liver isoform, mitochondrial (Q9UI32) | predicted | A | — | — |
Ligands
- GLN · Glutamine · in 1 record
Experiment against prediction
- 5U0K chain C against the predicted model Q9UI32: TM-score 0.99, RMSD 0.36 Å
- 5U0K chain C against the predicted model Q9UI32: TM-score 0.99, RMSD 0.36 Å
- 5U0K chain B against the predicted model Q9UI32: TM-score 0.99, RMSD 0.40 Å
- 5U0K chain B against the predicted model Q9UI32: TM-score 0.99, RMSD 0.40 Å
- 5U0K chain D against the predicted model Q9UI32: TM-score 0.99, RMSD 0.43 Å
- 5U0K chain E against the predicted model Q9UI32: TM-score 0.99, RMSD 0.44 Å
- 5U0K chain E against the predicted model Q9UI32: TM-score 0.99, RMSD 0.44 Å
- 5U0K chain F against the predicted model Q9UI32: TM-score 0.98, RMSD 0.47 Å
- 5U0K chain F against the predicted model Q9UI32: TM-score 0.98, RMSD 0.47 Å
- 4BQM chain A against the predicted model Q9UI32: TM-score 0.98, RMSD 1.18 Å
Elsewhere
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