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UniProt Q9U1F8

Pteridine reductase 1 (Q9U1F8)

Pteridine reductase 1 (UniProt Q9U1F8), EC 1.1.1.253: 4 experimental structures on GenesisL1, 4 ligands bound, 32 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q9U1F8
Protein
Pteridine reductase 1
EC
1.1.1.253
Experimental structures
4
Predicted models
0
Ligands
4
Pockets
32 · 4 records with a druggable one

Structures

4 records of Q9U1F8 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
1E7WOne active site, two modes of reduction correlate the mechanism of leishmania pteridine reductase…x-ray diffractionA, BNDP, MTX5 (best 0.73)
1E7WOne active site, two modes of reduction correlate the mechanism of leishmania pteridine reductase…x-ray diffractionA, BNDP, MTX5 (best 0.73)
1E92Pteridine reductase 1 from Leishmania major complexed with NADP+ and dihydrobiopterinx-ray diffractionA, B, C, DNAP, HBI11 (best 0.82)
1E92Pteridine reductase 1 from leishmania major complexed with NADP+ and dihydrobiopterinx-ray diffractionA, B, C, DNAP, HBI11 (best 0.82)

Ligands

  • HBI · 7,8-dihydrobiopterin · in 2 records
  • MTX · Methotrexate · in 2 records
  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · in 2 records
  • NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate · in 2 records

Elsewhere

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