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UniProt Q9U0E8

Dihydrofolate reductase-thymidylate synthase (Q9U0E8)

Dihydrofolate reductase-thymidylate synthase (UniProt Q9U0E8), EC 1.5.1.3: 2 experimental structures on GenesisL1, 2 ligands bound, 2 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q9U0E8
Protein
Dihydrofolate reductase-thymidylate synthase
EC
1.5.1.3
Experimental structures
2
Predicted models
0
Ligands
2
Pockets
2 · 1 record with a druggable one

Structures

2 records of Q9U0E8 in the MolNFT archive: 2 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
2BL9X-ray crystal structure of Plasmodium vivax dihydrofolate reductase in complex with pyrimethamine…x-ray diffractionANDP, CP62 (best 0.73)
2BL9X-ray crystal structure of plasmodium vivax dihydrofolate reductase in complex with pyrimethamine…x-ray diffractionA——

Ligands

  • CP6 · 5-(4-chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine · in 1 record
  • NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate · in 1 record

Elsewhere

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