UniProt Q9R186
Transient receptor potential cation channel subfamily V member 6 (Q9R186)
Transient receptor potential cation channel subfamily V member 6 (UniProt Q9R186): 25 experimental structures on GenesisL1, 6 ligands bound, 9 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q9R186
- Protein
- Transient receptor potential cation channel subfamily V member 6
- Experimental structures
- 25
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 9 · 1 record with a druggable one
Structures
25 records of Q9R186 in the MolNFT archive: 25 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5IWK | Structure of transient receptor potential (TRP) channel TRPV6 | x-ray diffraction | A | — | — |
| 5IWP | Structure of Transient Receptor Potential (TRP) channel TRPV6 in the presence of calcium | x-ray diffraction | A | CA, DTB | — |
| 5IWP | Structure of transient receptor potential (TRP) channel TRPV6 in the presence of calcium | x-ray diffraction | A | — | — |
| 5IWR | Structure of transient receptor potential (TRP) channel TRPV6 in the presence of barium | x-ray diffraction | A | — | — |
| 5IWT | Structure of transient receptor potential (TRP) channel TRPV6 in the presence of gadolinium | x-ray diffraction | A | — | — |
| 5WO6 | Crystal Structure of Transient Receptor Potential (TRP) channel TRPV6cryst | x-ray diffraction | A | CA, DTB | — |
| 5WO6 | Crystal structure of transient receptor potential (TRP) channel TRPV6CRYST | x-ray diffraction | A | CA, DTB | — |
| 5WO7 | Crystal structure of transient receptor potential (TRP) channel TRPV6* | x-ray diffraction | A | DTB, CA | — |
| 5WO8 | Crystal structure of transient receptor potential (TRP) channel TRPV6*-DEL1 | x-ray diffraction | A | DTB, CA | — |
| 5WO9 | Crystal structure of transient receptor potential (TRP) channel TRPV6* in the presence of calcium | x-ray diffraction | A | DTB, CA | — |
| 5WOA | Crystal Structure of Transient Receptor Potential (TRP) channel TRPV6* in the presence of Gadolinium | x-ray diffraction | A | GD | — |
| 5WOA | Crystal structure of transient receptor potential (TRP) channel TRPV6* in the presence of gadolinium | x-ray diffraction | A | GD | — |
| 6BOB | Cryo-EM structure of rat TRPV6* in nanodiscs | electron microscopy | A, B, C, D | — | — |
| 6D7O | Crystal Structure of Rat TRPV6* in complex with 2-Aminoethoxydiphenyl borate (2-APB) | x-ray diffraction | A | CA, FZ4, DTB | 9 (best 0.66) |
| 6D7O | Crystal structure of rat TRPV6* in complex with 2-aminoethoxydiphenyl borate (2-apb) | x-ray diffraction | A | CA, FZ4, DTB | — |
| 6D7P | Crystal structure of rat TRPV6*-Y466A | x-ray diffraction | A | CA, DTB | — |
| 6D7Q | Crystal Structure of Rat TRPV6*-Y466A in complex with 2-Aminoethoxydiphenyl borate (2-APB) | x-ray diffraction | A | FZ4, DTB, CA | — |
| 6D7Q | Crystal structure of rat TRPV6*-Y466A in complex with 2- aminoethoxydiphenyl borate (2-apb) | x-ray diffraction | A | FZ4, DTB, CA | — |
| 6D7V | Crystal structure of rat TRPV6*- in complex with brominated 2- aminoethoxydiphenyl borate (2-apb-br) | x-ray diffraction | A | FYY, CA | — |
| 6D7X | Crystal Structure of Rat TRPV6*-Y466A- in complex with brominated 2-Aminoethoxydiphenyl borate… | x-ray diffraction | A | CA, FYY, DTB | — |
| 6D7X | Crystal structure of rat TRPV6*-Y466A- in complex with brominated 2- aminoethoxydiphenyl borate… | x-ray diffraction | A | CA, FYY, DTB | — |
| 6E2G | Cryo-EM structure of rat TRPV6 in complex with calmodulin | electron microscopy | A, B, C, D | CA | — |
| 7D2K | Crystal structure of rat TRPV6 in complex with (4- phenylcyclohexyl)piperazine inhibitor Br-cis-22a | x-ray diffraction | A | CA, GQC | — |
| 7D2K | Crystal structure of rat TRPV6 in complex with (4- phenylcyclohexyl) piperazine inhibitor br-cis-22A | x-ray diffraction | A | CA, GQC | — |
| Q9R186 | AlphaFold monomer V2.0 prediction for transient receptor potential cation channel subfamily V… | — | — | — |
Ligands
- CA · Calcium ion · in 17 records
- DTB · 6-(5-methyl-2-oxo-imidazolidin-4-yl)-hexanoic acid · in 13 records
- FZ4 · 2-aminoethyl diphenylborinate · in 4 records
- FYY · 2-aminoethyl (4-bromophenyl)phenylborinate · in 3 records
- GD · Gadolinium atom · in 2 records
- GQC · 1-(5-bromanylpyridin-3-yl)-4-[4-(3-methylphenyl) cyclohexyl]piperazin-4-ium · in 2 records
Elsewhere
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