UniProt Q9QUH6
Ras/Rap GTPase-activating protein SynGAP (Q9QUH6)
Ras/Rap GTPase-activating protein SynGAP (UniProt Q9QUH6): 3 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9QUH6
- Protein
- Ras/Rap GTPase-activating protein SynGAP
- Experimental structures
- 3
- Predicted models
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
4 records of Q9QUH6 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3BXJ | Crystal Structure of the C2-GAP Fragment of synGAP | x-ray diffraction | A, B | — | — |
| 3BXJ | Crystal structure of the C2-gap fragment of syngap | x-ray diffraction | A, B | — | — |
| 8YM2 | Crystal structure of AIDA-1 PTB domain in complex with SynGAP NPxF motif | x-ray diffraction | B | — | — |
| Q9QUH6 | AlphaFold monomer V2.0 prediction for RAS/RAP GTPase-activating protein syngap (Q9QUH6) | predicted | A | — | 6 (best 0.80) |
Experiment against prediction
- 3BXJ chain A against the predicted model Q9QUH6: TM-score 0.93, RMSD 2.31 Å
- 3BXJ chain A against the predicted model Q9QUH6: TM-score 0.93, RMSD 2.31 Å
- 3BXJ chain B against the predicted model Q9QUH6: TM-score 0.92, RMSD 2.48 Å
- 3BXJ chain B against the predicted model Q9QUH6: TM-score 0.92, RMSD 2.48 Å
- 8YM2 chain B against the predicted model Q9QUH6: TM-score 0.46, RMSD 0.76 Å
Elsewhere
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