UniProt Q9P1U0
DNA-directed RNA polymerase I subunit RPA12 (Q9P1U0)
DNA-directed RNA polymerase I subunit RPA12 (UniProt Q9P1U0): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q9P1U0
- Protein
- DNA-directed RNA polymerase I subunit RPA12
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
7 records of Q9P1U0 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7OB9 | Cryo-EM structure of human RNA polymerase I in elongation state | electron microscopy | I | ZN | — |
| 7OBA | Cryo-EM structure of human RNA polymerase I in complex with RRN3 | electron microscopy | I | ZN | — |
| 7OBB | Cryo-EM structure of human RNA polymerase I open complex | electron microscopy | I | ZN | — |
| 7VBA | Structure of the pre state human RNA Polymerase I Elongation Complex | electron microscopy | I | — | — |
| 8A43 | Human RNA polymerase I | electron microscopy | I | — | 1 (best 0.78) |
| 8A43 | Human RNA polymerase I | electron microscopy | I | — | — |
| Q9P1U0 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase I subunit RPA12 (Q9P1U0) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 3 records
Experiment against prediction
- 7OB9 chain I against the predicted model Q9P1U0: TM-score 0.71, RMSD 1.87 Å
- 8A43 chain I against the predicted model Q9P1U0: TM-score 0.60, RMSD 2.38 Å
- 8A43 chain I against the predicted model Q9P1U0: TM-score 0.60, RMSD 2.38 Å
- 7VBA chain I against the predicted model Q9P1U0: TM-score 0.52, RMSD 2.95 Å
- 7OBB chain I against the predicted model Q9P1U0: TM-score 0.45, RMSD 1.16 Å
- 7OBA chain I against the predicted model Q9P1U0: TM-score 0.44, RMSD 1.27 Å
Elsewhere
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