UniProt Q9P013
Spliceosome-associated protein CWC15 homolog (Q9P013)
Spliceosome-associated protein CWC15 homolog (UniProt Q9P013): 20 experimental structures and 1 predicted model on GenesisL1, 19 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9P013
- Protein
- Spliceosome-associated protein CWC15 homolog
- Experimental structures
- 20
- Predicted models
- 1
- Pockets
- 19 · 4 records with a druggable one
Structures
21 records of Q9P013 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5MQF | Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex) | electron microscopy | R | — | — |
| 5XJC | Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom | electron microscopy | P | — | — |
| 5Z58 | Cryo-EM structure of a human activated spliceosome (early bact) at 4.9 ångström. | electron microscopy | P | — | — |
| 6FF4 | human Bact spliceosome core structure | electron microscopy | R | — | 4 (best 0.88) |
| 6FF4 | Human bact spliceosome core structure | electron microscopy | R | — | — |
| 6FF7 | Human bact spliceosome core structure | electron microscopy | R | — | — |
| 6ICZ | Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 ångström | electron microscopy | P | — | — |
| 6ID0 | Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9… | electron microscopy | P | — | — |
| 6ID0 | Cryo-EM structure of a human intron lariat spliceosome prior to PRP43 loaded (ILS1 complex) at 2.9… | electron microscopy | P | — | — |
| 6ID1 | Cryo-EM structure of a human intron lariat spliceosome after PRP43 loaded (ILS2 complex) at 2.9… | electron microscopy | P | — | — |
| 6ZYM | Human C Complex Spliceosome - High-resolution CORE | electron microscopy | R | — | 4 (best 0.85) |
| 6ZYM | Human C complex spliceosome - high-resolution core | electron microscopy | R | — | — |
| 7AAV | Human pre-bact-2 spliceosome core structure | electron microscopy | R | — | — |
| 7ABI | Human pre-bact-2 spliceosome | electron microscopy | R | — | — |
| 7DVQ | Cryo-EM structure of the activated human minor spliceosome (minor bact complex) | electron microscopy | P | — | — |
| 7W59 | The cryo-EM structure of human pre-C*-I complex | electron microscopy | P | — | — |
| 7W5A | The cryo-EM structure of human pre-C*-II complex | electron microscopy | P | — | — |
| 7W5A | The cryo-EM structure of human pre-C*-II complex | electron microscopy | P | — | — |
| 8C6J | Human spliceosomal PM5 C* complex | electron microscopy | P | — | 7 (best 0.91) |
| 8I0U | The cryo-EM structure of human Bact-IV complex | electron microscopy | P | — | 4 (best 0.88) |
| Q9P013 | AlphaFold monomer V2.0 prediction for spliceosome-associated protein CWC15 homolog (Q9P013) | predicted | A | — | — |
Experiment against prediction
- 6ICZ chain P against the predicted model Q9P013: TM-score 0.82, RMSD 2.10 Å
- 8C6J chain P against the predicted model Q9P013: TM-score 0.81, RMSD 2.13 Å
- 7W59 chain P against the predicted model Q9P013: TM-score 0.81, RMSD 2.30 Å
- 7W5A chain P against the predicted model Q9P013: TM-score 0.81, RMSD 2.32 Å
- 7W5A chain P against the predicted model Q9P013: TM-score 0.81, RMSD 2.32 Å
- 5XJC chain P against the predicted model Q9P013: TM-score 0.80, RMSD 2.23 Å
- 6ID0 chain P against the predicted model Q9P013: TM-score 0.79, RMSD 2.42 Å
- 6ID0 chain P against the predicted model Q9P013: TM-score 0.79, RMSD 2.42 Å
- 6ID1 chain P against the predicted model Q9P013: TM-score 0.79, RMSD 2.46 Å
- 5Z58 chain P against the predicted model Q9P013: TM-score 0.78, RMSD 2.31 Å
Elsewhere
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