UniProt Q9NZD1
G-protein coupled receptor family C group 5 member D (Q9NZD1)
G-protein coupled receptor family C group 5 member D (UniProt Q9NZD1): 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 16 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9NZD1
- Protein
- G-protein coupled receptor family C group 5 member D
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 16 · 2 records with a druggable one
Structures
3 records of Q9NZD1 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8YZK | Orphan receptor GPRC5D in complex with scFv150-18 | electron microscopy | A, B | — | 10 (best 0.76) |
| 9IMA | Cryo-EM structure for the GPRC5D complexed with Talquetamab Fab | electron microscopy | B, A | CLR | 6 (best 0.72) |
| Q9NZD1 | AlphaFold monomer V2.0 prediction for G-protein coupled receptor family C group 5 member D (Q9NZD1) | predicted | A | — | — |
Ligands
- CLR · Cholesterol · in 1 record
Experiment against prediction
- 9IMA chain A against the predicted model Q9NZD1: TM-score 0.97, RMSD 1.24 Å
- 9IMA chain B against the predicted model Q9NZD1: TM-score 0.96, RMSD 1.26 Å
- 8YZK chain A against the predicted model Q9NZD1: TM-score 0.92, RMSD 2.16 Å
- 8YZK chain B against the predicted model Q9NZD1: TM-score 0.92, RMSD 2.16 Å
- 8YZK chain B against the predicted model P0ABE7: TM-score 0.29, RMSD 4.13 Å
- 8YZK chain A against the predicted model P0ABE7: TM-score 0.28, RMSD 4.68 Å
Elsewhere
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