UniProt Q9NY46
Sodium channel protein type 3 subunit alpha (Q9NY46)
Sodium channel protein type 3 subunit alpha (UniProt Q9NY46): 4 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 98 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q9NY46
- Protein
- Sodium channel protein type 3 subunit alpha
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 98 · 5 records with a druggable one
Structures
5 records of Q9NY46 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7W77 | cryo-EM structure of human NaV1.3/beta1/beta2-bulleyaconitineA | electron microscopy | D | NAG, BMA, 9Z9, 6OU, 966 | 20 (best 0.86) |
| 7W77 | Cryo-EM structure of human NAV1.3/BETA1/BETA2-bulleyaconitinea | electron microscopy | D | NAG, BMA, 9Z9, 6OU, 966 | 20 (best 0.86) |
| 7W7F | Cryo-EM structure of human NaV1.3/beta1/beta2-ICA121431 | electron microscopy | D | NAG, BMA, 6OU, 8DE, 9Z9 | 19 (best 0.86) |
| 7W7F | Cryo-EM structure of human NAV1.3/BETA1/BETA2-ICA121431 | electron microscopy | D | NAG, BMA, 6OU, 8DE, 9Z9 | 19 (best 0.86) |
| Q9NY46 | AlphaFold monomer V2.0 prediction for sodium channel protein type 3 subunit alpha (Q9NY46) | predicted | A | — | 20 (best 0.86) |
Ligands
- 6OU · [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate · in 4 records
- 9Z9 · (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en · in 4 records
- BMA · beta-D-mannopyranose · in 4 records
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
- 8DE · 2,2-diphenyl-~{N}-[4-(1,3-thiazol-2-ylsulfamoyl) phenyl]ethanamide · in 2 records
- 966 · [(1S,2R,3R,4R,5R,6S,8R,9S,13S,16S,17R,18R)-11-ethyl-5-hydroxy-6,16,18-trimethoxy-4-(4-methoxybenzoyl)-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03, 8.013,17]nonadecan-8-yl] acetate · in 2 records
Experiment against prediction
- 7W77 chain D against the predicted model Q9NY46: TM-score 0.98, RMSD 1.90 Å
- 7W77 chain D against the predicted model Q9NY46: TM-score 0.98, RMSD 1.90 Å
- 7W7F chain D against the predicted model Q9NY46: TM-score 0.97, RMSD 1.95 Å
- 7W7F chain D against the predicted model Q9NY46: TM-score 0.97, RMSD 1.95 Å
Elsewhere
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