UniProt Q9NY33
Dipeptidyl peptidase 3 (Q9NY33)
Dipeptidyl peptidase 3 (UniProt Q9NY33), EC 3.4.14.4: 16 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NY33
- Protein
- Dipeptidyl peptidase 3
- EC
- 3.4.14.4
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 11 · 2 records with a druggable one
Structures
17 records of Q9NY33 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3FVY | Crystal structure of human Dipeptidyl Peptidase III | x-ray diffraction | A | — | — |
| 3FVY | Crystal structure of human dipeptidyl peptidase III | x-ray diffraction | A | — | — |
| 3T6B | Structure of human DPPIII in complex with the opioid peptide Tynorphin, at 2.4 Angstroms | x-ray diffraction | A, B | — | — |
| 3T6B | Structure of human dppiii in complex with the opioid peptide tynorphin, at 2.4 ångströms | x-ray diffraction | A, B | — | — |
| 3T6J | Structure of human DPPIII in complex with the opioid peptide Tynorphin, at 3.0 Angstroms | x-ray diffraction | A | — | — |
| 3T6J | Structure of human dppiii in complex with the opioid peptide tynorphin, at 3.0 ångströms | x-ray diffraction | A | — | — |
| 5E2Q | Structure of human DPP3 in complex with angiotensin-II | x-ray diffraction | A | — | — |
| 5E33 | Structure of human DPP3 in complex with met-enkephalin | x-ray diffraction | A | — | — |
| 5E3A | Structure of human DPP3 in complex with opioid peptide leu-enkephalin | x-ray diffraction | A | ZN, MG, K | 7 (best 0.85) |
| 5E3A | Structure of human DPP3 in complex with opioid peptide leu-enkephalin | x-ray diffraction | A | — | — |
| 5E3C | Structure of human DPP3 in complex with hemorphin like opioid peptide IVYPW | x-ray diffraction | A | ZN, MG, K | 4 (best 0.87) |
| 5E3C | Structure of human DPP3 in complex with hemorphin like opioid peptide ivypw | x-ray diffraction | A | — | — |
| 5EGY | Structure of ligand free human DPP3 in closed form. | x-ray diffraction | A | — | — |
| 5EHH | Structure of human DPP3 in complex with endomorphin-2. | x-ray diffraction | A | ZN, MG, K | — |
| 5EHH | Structure of human DPP3 in complex with endomorphin-2. | x-ray diffraction | A | — | — |
| 7OUP | Structure of human DPP3 in complex with a hydroxyethylene transition state peptidomimetic | x-ray diffraction | A | 1QI, ZN, K, MG | — |
| Q9NY33 | AlphaFold monomer V2.0 prediction for dipeptidyl peptidase 3 (Q9NY33) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7OUP chain A against the predicted model Q9NY33: TM-score 1.00, RMSD 0.36 Å
- 3T6B chain A against the predicted model Q9NY33: TM-score 1.00, RMSD 0.42 Å
- 3T6B chain A against the predicted model Q9NY33: TM-score 1.00, RMSD 0.42 Å
- 3T6B chain B against the predicted model Q9NY33: TM-score 1.00, RMSD 0.43 Å
- 3T6B chain B against the predicted model Q9NY33: TM-score 1.00, RMSD 0.43 Å
- 5EHH chain A against the predicted model Q9NY33: TM-score 1.00, RMSD 0.49 Å
- 5EHH chain A against the predicted model Q9NY33: TM-score 1.00, RMSD 0.49 Å
- 5EGY chain A against the predicted model Q9NY33: TM-score 1.00, RMSD 0.46 Å
- 5E3C chain A against the predicted model Q9NY33: TM-score 1.00, RMSD 0.58 Å
- 5E3C chain A against the predicted model Q9NY33: TM-score 1.00, RMSD 0.58 Å
Elsewhere
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