UniProt Q9NVV4
Poly(A) RNA polymerase (Q9NVV4)
Poly(A) RNA polymerase (UniProt Q9NVV4), EC 2.7.7.19: 2 experimental structures and 1 predicted model on GenesisL1, 21 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NVV4
- Protein
- Poly(A) RNA polymerase
- EC
- 2.7.7.19
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 21 · 2 records with a druggable one
Structures
3 records of Q9NVV4 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3PQ1 | Crystal structure of human mitochondrial poly(A) polymerase (PAPD1) | x-ray diffraction | A, B | — | 13 (best 0.60) |
| 3PQ1 | Crystal structure of human mitochondrial POLY(A) polymerase (PAPD1) | x-ray diffraction | A, B | — | — |
| Q9NVV4 | AlphaFold monomer V2.0 prediction for POLY(A) RNA polymerase, mitochondrial (Q9NVV4) | predicted | A | — | 8 (best 0.74) |
Experiment against prediction
- 3PQ1 chain A against the predicted model Q9NVV4: TM-score 0.97, RMSD 1.26 Å
- 3PQ1 chain A against the predicted model Q9NVV4: TM-score 0.97, RMSD 1.26 Å
- 3PQ1 chain B against the predicted model Q9NVV4: TM-score 0.95, RMSD 1.73 Å
- 3PQ1 chain B against the predicted model Q9NVV4: TM-score 0.95, RMSD 1.73 Å
Elsewhere
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